DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment galene and Kcnk7

DIOPT Version :9

Sequence 1:	NP_612084.1	Gene:	galene / 38133	FlyBaseID:	FBgn0035192	Length:	729	Species:	Drosophila melanogaster
Sequence 2:	XP_002728904.1	Gene:	Kcnk7 / 499303	RGDID:	1565025	Length:	316	Species:	Rattus norvegicus

Alignment Length:	154	Identity:	41/154 - (26%)
Similarity:	67/154 - (43%)	Gaps:	32/154 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 W-KVLTCIVSHVLLVLLVVSYCVGGAYLFQHLERPHELEVKRDIQ-NLRVNLTENIWLLSDDAVV 94
            | :.|..:::|:|.:.|       ||.:.|.||.|..|.::..:| .|.....|:...|..:|
  Rat     7 WARYLLLVMAHLLAMGL-------GAVVLQALEGPPALHLQVQLQAELAAFQAEHRACLPPEA-- 62

  Fly    95 LRESDWMANVSKHLANFEKQILTAIKADG----WDGDEDLRKSQWTFAGSLFYSIIVITTIGYGH 155
                         |......:||| :|.|    .:|.|   .|.|....:|.::..::||.|||.
  Rat    63 -------------LEELLGAVLTA-QAHGVSSLGNGSE---TSNWDLPSALLFTASILTTTGYGR 110

  Fly   156 ISPRTDWGKVTTIFYAIVGIPLML 179
            ::|.:..||...:.||.:|:|..|
  Rat   111 MAPFSSGGKAFCVVYAALGLPASL 134

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
galene	NP_612084.1	Ion_trans_2	<134..189	CDD:285168	15/46 (33%)
		NESP55	341..586	CDD:115071
		Ion_trans	<621..709	CDD:278921
		Ion_trans_2	626..706	CDD:285168
Kcnk7	XP_002728904.1	Ion_trans_2	<88..144	CDD:400301	16/47 (34%)
Kcnk7	XP_002728904.1	Ion_trans_2	178..>225	CDD:400301
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1418
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	128	1.000	Inparanoid score	I4566
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.950