DRSC/TRiP Functional Genomics Resources

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Protein Alignment galene and KCNK3

DIOPT Version :10

Sequence 1:NP_612084.1 Gene:galene / 38133 FlyBaseID:FBgn0035192 Length:729 Species:Drosophila melanogaster
Sequence 2:NP_002237.1 Gene:KCNK3 / 3777 HGNCID:6278 Length:394 Species:Homo sapiens


Alignment Length:58 Identity:19/58 - (32%)
Similarity:27/58 - (46%) Gaps:12/58 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   362 GCEAGDN---GEMRKDDDKEEETRSFE----GEAYRESKRIRDAIAENLSRVHMAQSQ 412
            |.:.|||   .|:||.|:  .:|.|.|    .:..|.|:.:|   ||..|:.....||
Human   134 GKKTGDNSTKAEIRKPDN--SKTTSLEKQKAADQGRGSQSLR---AEKTSKSDDRPSQ 186

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
galeneNP_612084.1 Ion_trans_2 115..189 CDD:462301
Ion_trans_2 626..706 CDD:462301
KCNK3NP_002237.1 Ion_trans_2 <73..132 CDD:462301
Selectivity filter 1. /evidence=ECO:0000305|PubMed:26919430 93..98
Ion_trans_2 167..243 CDD:462301 8/23 (35%)
Selectivity filter 2. /evidence=ECO:0000305|PubMed:26919430 199..204
X-gate. /evidence=ECO:0000269|PubMed:32499642 243..248
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 266..286
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 338..357
Blue background indicates that the domain is not in the aligned region.

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