DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment galene and Kcnk9

DIOPT Version :9

Sequence 1:	NP_612084.1	Gene:	galene / 38133	FlyBaseID:	FBgn0035192	Length:	729	Species:	Drosophila melanogaster
Sequence 2:	XP_006520831.1	Gene:	Kcnk9 / 223604	MGIID:	3521816	Length:	604	Species:	Mus musculus

Alignment Length:	213	Identity:	65/213 - (30%)
Similarity:	94/213 - (44%)	Gaps:	51/213 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 HMLEPAKPQRGRCVAA-----------ICFSWKVLTCI----VSHVLLVLLVVSYCVGGAYLFQH 61
            |.|:....:||..|:|           :.||......:    |..:.|:....:|.:.||.:|..
Mouse   166 HRLQLRLHRRGGLVSAALHWDSRGLVQLPFSISFFAAMKRQNVRTLSLIACTFTYLLVGAAVFDA 230

  Fly    62 LERPHELEVKRDIQNLRVNLTENIWLLSDD-----AVVLRESDWMANVSKHLANFEKQILTAIKA 121
            ||..||:..:..::...|.|.....:.|||     .|:|:.....|.|
Mouse   231 LESDHEMREEEKLKAEEVRLRGKYNISSDDYQQLELVILQSEPHRAGV----------------- 278

  Fly   122 DGWDGDEDLRKSQWTFAGSLFYSIIVITTIGYGHISPRTDWGKVTTIFYAIVGIPLMLICLSNIG 186
                        ||.||||.:::|.|||||||||.:|.||.||...:|||::||||.|:...::|
Mouse   279 ------------QWKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPLTLVMFQSLG 331

  Fly   187 DVMATSFRFLYWRI--CC 202
            :.|.|..|:|..||  ||
Mouse   332 ERMNTFVRYLLKRIKKCC 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
galene	NP_612084.1	Ion_trans_2	<134..189	CDD:285168	30/54 (56%)
		NESP55	341..586	CDD:115071
		Ion_trans	<621..709	CDD:278921
		Ion_trans_2	626..706	CDD:285168
Kcnk9	XP_006520831.1	Ion_trans_2	<279..334	CDD:400301	30/54 (56%)
Kcnk9	XP_006520831.1	Ion_trans_2	372..445	CDD:400301
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2198
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.860