DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment galene and twk-10

DIOPT Version :9

Sequence 1:	NP_612084.1	Gene:	galene / 38133	FlyBaseID:	FBgn0035192	Length:	729	Species:	Drosophila melanogaster
Sequence 2:	NP_001300134.1	Gene:	twk-10 / 192080	WormBaseID:	WBGene00006665	Length:	429	Species:	Caenorhabditis elegans

Alignment Length:	181	Identity:	55/181 - (30%)
Similarity:	86/181 - (47%)	Gaps:	23/181 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 HVLLVLLVVSYCVGGAYLFQHLERPHELEVKRDIQN----LRVNLTENIWLL-----SDDAVVLR 96
            ||.|:||.:.|...||..|.:.|.|.|..:.|.::.    ||....||:..:     ||:..|..
Worm    39 HVGLILLCILYVHFGALFFMYSESPEEQRILRRVEKRYDILRETFLENVNRVKLEDFSDERRVNE 103

  Fly    97 E-SDWMANVSKHLANFEKQILTAIKADGWDGDEDLRKSQ------WTFAGSLFYSIIVITTIGYG 154
            . |..:.:.|||:.   |.....:.|:.:|   .|..||      ||...||.::...|..:|||
Worm   104 SISRLIDDYSKHMF---KLFTNPVAANMFD---CLFYSQSNYTPLWTTDSSLLFTATTIIPVGYG 162

  Fly   155 HISPRTDWGKVTTIFYAIVGIPLMLICLSNIGDVMATSF-RFLYWRICCYV 204
            :|:|.|..|::....||..||||.|:.:|::|...|.:| :|.:..|..::
Worm   163 YIAPLTSTGRIVLCIYAAFGIPLALVMMSDVGKFFADAFVKFFHENITAFM 213

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
galene	NP_612084.1	Ion_trans_2	<134..189	CDD:285168	22/60 (37%)
		NESP55	341..586	CDD:115071
		Ion_trans	<621..709	CDD:278921
		Ion_trans_2	626..706	CDD:285168
twk-10	NP_001300134.1	Ion_trans_2	<143..199	CDD:285168	21/55 (38%)
twk-10	NP_001300134.1	Ion_trans_2	218..291	CDD:285168
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1418
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810