DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment galene and twk-4

DIOPT Version :9

Sequence 1:	NP_612084.1	Gene:	galene / 38133	FlyBaseID:	FBgn0035192	Length:	729	Species:	Drosophila melanogaster
Sequence 2:	NP_001343566.1	Gene:	twk-4 / 192079	WormBaseID:	WBGene00006659	Length:	418	Species:	Caenorhabditis elegans

Alignment Length:	153	Identity:	44/153 - (28%)
Similarity:	80/153 - (52%)	Gaps:	12/153 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 HVLLVLLVVSYCVGGAYLFQHLERPHELEVKRDIQNLRVNLTENIWLLSDDAVVLRESDWMANVS 105
            |::|:...|:|.:.|||||..:|...||:..:....:..|...|::..|:.:|        |:|.
Worm    91 HLVLIFATVAYIIAGAYLFTKIEHQAELDRYQSYHTIYRNFINNLYQSSNRSV--------ADVE 147

  Fly   106 KHLANFEKQILTAIKADGWDGDEDL---RKSQWTFAGSLFYSIIVITTIGYGHISPRTDWGKVTT 167
            ..:..|......|.| :|....:.|   ..|:|:...::|::..|:|:||||::.|.:..||:..
Worm   148 NLIDTFTSINFRAFK-EGLKPTDFLVPQETSRWSMISAIFFTTTVLTSIGYGNLIPISTGGKIFC 211

  Fly   168 IFYAIVGIPLMLICLSNIGDVMA 190
            :.|||.||||.|:.::::...:|
Worm   212 VGYAIFGIPLTLVTIADLAKFVA 234

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
galene	NP_612084.1	Ion_trans_2	<134..189	CDD:285168	19/54 (35%)
		NESP55	341..586	CDD:115071
		Ion_trans	<621..709	CDD:278921
		Ion_trans_2	626..706	CDD:285168
twk-4	NP_001343566.1	Ion_trans_2	<178..235	CDD:311712	20/57 (35%)
twk-4	NP_001343566.1	Ion_trans_2	255..329	CDD:311712
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1418
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D542195at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820