Protein Alignment galene and twk-40

DIOPT Version :9

• Sequence 1: NP_612084.1
• Gene: galene / 38133
• FlyBaseID: FBgn0035192
• Length: 729
• Species: Drosophila melanogaster
• Sequence 2: NP_001255206.1
• Gene: twk-40 / 189006
• WormBaseID: WBGene00006691
• Length: 436
• Species: Caenorhabditis elegans
• Alignment Length: 703
• Identity: 114/703 - (16%)
• Similarity: 186/703 - (26%)
• Gaps: 413/703 - (58%)

  Fly    31 SWKVLT-CIVSHVLLVLLVVSYCVGGAYLFQHLERPHELEVK-RDIQNLRVN---LTENIWLLSD 90
            :||... .|::||.|::|.|.|...||:||..||:|:|:||: |:|:...::   :.|::|
 Worm    46 TWKTYARIILAHVSLIVLSVVYVGFGAFLFYQLEQPNEVEVRARNIERFNIHKRQMIEHLW---- 106

  Fly    91 DAVVLRESDWMANVSKHLANFEKQILTAIKADGWD-----------GDEDLRKSQWTFAGSLFYS 144
               .:|||....:|.:.||......:|.|..:.:|           |.|| ....||:..:||::
 Worm   107 ---EMRESGIGQHVVEDLAVKYVDNVTRILFEAFDTHCIGAKHLRPGGED-EDYNWTYMTALFFT 167

  Fly   145 IIVITTIGYGHISPRTDWGKVTTIFYAIVGIPLMLICLSNIGDVMATSFRFLY-WRICCYVCTRT 208
            ..::||||||:::|.|..||:..|.||:.|:||:||.:::||..::.:...|| |
 Worm   168 TTLLTTIGYGNLTPVTGRGKLLCILYALFGVPLILITVADIGKFLSENIVQLYTW---------- 222

  Fly   209 AKRPRNARSRQRSMRSQRHARSQPPPSFRRSMKMTQRSGNDSGLGPSMGHAYSDPDLRTMGRGYD 273
                                       :|:.
 Worm   223 ---------------------------YRKL---------------------------------- 226

  Fly   274 DREFGHRSSGGGRNRRQQQQQHLHHDPRQRHTIYGDGYETQTLNRSNRYSSRQRQRDRMRDRHTV 338
                                                                             
 Worm   227 ----------------------------------------------------------------- 226

  Fly   339 ERERYSRSHLDAGSIEDFGDMQPPAKRAASVRSVRSPHNQESSKASRELHRLHSAPGRSRAKSVD 403
             ||:.|                   |:..||.|.:...|:|.
 Worm   227 -REKCS-------------------KQKYSVISSKDDKNKEG----------------------- 248

  Fly   404 PRHVSSHYEDVDEDVVRKTPIIPNRYALDDFGGNRRQAAPRSQSMPRSAHQRQRQKDRERERSPQ 468
                     |::.|
 Worm   249 ---------DLNLD--------------------------------------------------- 253

  Fly   469 PPPQSSYRQQHDRRAGSLGRQSSRYGNHLELPDYDAPPPGRDHRRDRRGHSQGRYEDYVEESFDE 533
                                       ||                          |:|:.
 Worm   254 ---------------------------HL--------------------------ENYIS----- 260

  Fly   534 GSLYGDNNYEDYPPERHHSRSREPKRNRRRERAERLPPSPRIMSPMGFPVQRQIRRRPSYDYDDD 598
                                                                             
 Worm   261 ----------------------------------------------------------------- 260

  Fly   599 DSMYGDEYGDYGDLLPKDRPVPIWLCVFLVVSYILGGAVLFAYWENWSFLDSAYFCFITLTTIGF 663
                                :||:|.|.:::|||..|||:.:.||.|.|....||.|||:||:||
 Worm   261 --------------------IPIFLIVAILLSYITFGAVVLSMWEGWDFFSGFYFSFITMTTVGF 305

  Fly   664 GDFVPAKGVKDESEQSIAYCSLYLLFGIALLAMSFNLVQEEFIANVKEVARRL 716
            ||.||.|    .....:..|  |::.|:::..|..:||..::|..:....|.:
 Worm   306 GDIVPLK----REYYILDLC--YIIIGLSITTMCIDLVGIQYIRKMHYFGRAI 352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
galene	NP_612084.1	Ion_trans_2	<134..189	CDD:285168	24/54 (44%)
		NESP55	341..586	CDD:115071	14/244 (6%)
		Ion_trans	<621..709	CDD:278921	34/87 (39%)
		Ion_trans_2	626..706	CDD:285168	30/79 (38%)
twk-40	NP_001255206.1	Ion_trans_2	<174..214	CDD:285168	18/39 (46%)
		Ion_trans_2	269..343	CDD:285168	30/79 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D542195at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.020