Protein Alignment galene and twk-39

DIOPT Version :9

• Sequence 1: NP_612084.1
• Gene: galene / 38133
• FlyBaseID: FBgn0035192
• Length: 729
• Species: Drosophila melanogaster
• Sequence 2: NP_001076639.1
• Gene: twk-39 / 182864
• WormBaseID: WBGene00006690
• Length: 676
• Species: Caenorhabditis elegans
• Alignment Length: 807
• Identity: 207/807 - (25%)
• Similarity: 318/807 - (39%)
• Gaps: 284/807 - (35%)

  Fly    21 RGRCVAAICFSWKVLTCIVSHVLLVLLVVSYCVGGAYLFQHLERPHELEVKRDIQNLRVNLTENI 85
            |..|:....|........::||.|..||..|.|.||::||.:|.|:||.::..::|..:.:.::|
 Worm     6 RSFCLKFTTFVKSATIFTITHVGLCFLVALYAVAGAFMFQAVEYPYELGLQGKVKNASLKVVDDI 70

  Fly    86 WL------LSDDAVVLRESDWMANVSKHLANFEKQILTAIKADGWD-GDEDLRKSQWTFAGSLFY 143
            :.      :.::..|..||.|.      |..||..::.|:..:|:| .||:....||||:|:|.|
 Worm    71 YRFINRKNVIEETAVKNESQWA------LKEFEMLLVHAMNFEGYDEHDEERPTFQWTFSGALLY 129

  Fly   144 SIIVITTIGYGHISPRTDWGKVTTIFYAIVGIPLMLICLSNIGDVMATSFRFLYWRICCYVCTRT 208
            ||.|.||||||||.|:||.|::.||.|:|:||||||:||:||.:.:|..|.::|:::||..|
 Worm   130 SITVFTTIGYGHICPKTDTGRLLTILYSILGIPLMLLCLANIAETLAQVFTYIYFKLCCAYC--- 191

  Fly   209 AKRPRNARSRQRSMRSQRHARSQPPPSFRRSMKMTQRSGNDSGLGPSMGHAYSDPDLRTMGRGYD 273
                |..::|:|..|:....|..|..:.......:.||
 Worm   192 ----RWQKNRRRVRRAALSFRYHPNAAVNVRRVQSSRS--------------------------- 225

  Fly   274 DREFGHRSSGGGRNRRQQQQQHLHHDPRQRHTIYGDGYETQTLNRSNRYSSRQRQRDRMRDRHTV 338
                                                   .|..|...|::|..|.|.|..|..:|
 Worm   226 ---------------------------------------NQRYNTVRRHASLNRSRTRSNDTKSV 251

  Fly   339 ER-ERYSRSHLDAGSIEDFGDMQPPAKRAASVRSVRSP-----------------HNQESSKASR 385
            .. .||..::........|..|..|.:|..|.:| |||                 |.|:|:.|.
 Worm   252 RSFNRYDSTNTQPVQPPRFDTMSLPGRRKISTQS-RSPNGTMPRLPNFPQPKRGAHLQKSNTAI- 314

  Fly   386 ELHRLHSAPGRSR----AKSVDPRH-------VSSHYEDVDEDVVRKTPIIPNRYALDDFGGN-- 437
            .:.:|::...|||    |.|..|..       |.:.::. ||.||          .|..:||:
 Worm   315 NMEQLYTDEKRSRRGRHAVSESPAREYKGGLLVRAQHQP-DEGVV----------DLKAYGGSAA 368

  Fly   438 ----------RRQAAPRSQSMPRSAHQRQRQK------DRERERS--------PQPPPQ--SSYR 476
                      ||..|    ::|.....|.|.:      |:..|.|        .|.||:  :|.|
 Worm   369 AFHDLVTRKPRRDDA----AVPNVIISRTRDEDVKSDPDKTEETSMSLTDDEDMQKPPRRNNSAR 429

  Fly   477 QQHDR----------RAGSLGRQSSRYGNHLELPDYDAPPPGRDHRRDRRGHSQGRYEDYVEESF 531
            :..::          :..|:...:||     .|.|.|    ||.:|.||            .|..
 Worm   430 ELREKEMMMMNSLNHKQPSMDSSTSR-----RLRDID----GRSYRSDR------------SERS 473

  Fly   532 DEGSLYGDNNYEDYPPERHHSRSREPKRNRRRERAERLPPSPRIMSPMGFPVQRQIRRRPSYDYD 596
            ||.||              ||..|...||:.:
 Worm   474 DEMSL--------------HSLRRNGHRNQEK--------------------------------- 491

  Fly   597 DDDSMYGDEYGDYGDLLPKDRPVPIWLCVFLVVSYILGGAVLFAYWENWSFLDSAYFCFITLTTI 661
                                .||.:.:|:  |.::|.|||.||::||||:..|.||:|||||:||
 Worm   492 --------------------MPVSVGICI--VFAFISGGAWLFSWWENWNGFDGAYYCFITLSTI 534

  Fly   662 GFGDFVPAKGVKDESEQSIAYCSLYLLFGIALLAMSFNLVQEEFIANVKEVARRLGIL------- 719
            ||||.||.:.:.:.|::.:..|:||||||:||:||.|.|:|::.:...:.:.:::|||
 Worm   535 GFGDIVPGQALDEGSQEKLVVCALYLLFGMALIAMCFKLMQDDVVQKARWLGQKIGILARPFELS 599

  Fly   720 -----------------KDDDDEQDED 729
                             :|:..|.:.|
 Worm   600 REIAKHAIFLFGYSVSIRDESSESESD 626

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
galene	NP_612084.1	Ion_trans_2	<134..189	CDD:285168	36/54 (67%)
		NESP55	341..586	CDD:115071	65/310 (21%)
		Ion_trans	<621..709	CDD:278921	43/87 (49%)
		Ion_trans_2	626..706	CDD:285168	42/79 (53%)
twk-39	NP_001076639.1	Ion_trans_2	<120..177	CDD:285168	36/56 (64%)
		Ion_trans_2	498..580	CDD:285168	43/83 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156533
Domainoid	1	1.000	100	1.000	Domainoid score	I4417
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D542195at33208
OrthoFinder	1	1.000	-	-		FOG0016750
OrthoInspector	1	1.000	-	-		oto17350
orthoMCL	1	0.900	-	-		OOG6_113981
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2863
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.850