DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment galene and unc-58

DIOPT Version :9

Sequence 1:	NP_612084.1	Gene:	galene / 38133	FlyBaseID:	FBgn0035192	Length:	729	Species:	Drosophila melanogaster
Sequence 2:	NP_001360793.1	Gene:	unc-58 / 181224	WormBaseID:	WBGene00006792	Length:	616	Species:	Caenorhabditis elegans

Alignment Length:	233	Identity:	61/233 - (26%)
Similarity:	106/233 - (45%)	Gaps:	51/233 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 KVLTCIVSHVLLVLLVVSYCVGGAYLFQHLERPHELEVKRD----IQNLRVNLTENIWLLSDDA- 92
            |.:..:..||:||.:::.|...||::...||...||..:..    :.||..|.|...|.:.::|
Worm   187 KYIKILTPHVILVSVLIGYLCLGAWILMLLETRTELLARSKKLVRLTNLMSNFTAESWKMLNNAQ 251

  Fly    93 ---VVLRESDWMANVSKHLANFEKQILTAIKADGWDGDEDLRK------------SQWTFAGSLF 142
               ..:.|.:|.|...:.:....:.:         |....:|:            ::|||..::.
Worm   252 HGVSNMDEGEWAATFREWMVRVSETV---------DDRRPIRRELNRPDDLSNMHNKWTFPTAIL 307

  Fly   143 YSIIVITTIGYGHISPRTDWGKVTTIFYAIVGIPLMLICLSNIGDVMA-TSFRFL-YWRICCYVC 205
            |.:.|:||.|||.:|..||.|||.::.:|:||||||.|..::||..:: |..:|: :|.
Worm   308 YVLTVLTTCGYGEVSVDTDVGKVFSVAFALVGIPLMFITAADIGKFLSETLLQFVSFWN------ 366

  Fly   206 TRTAKRPRNARSRQRSMRSQRHARSQPPPSFRRSMKMT 243
                   |:.|..::.|...||.|       |:|::.|
Worm   367 -------RSVRKVKQWMSRIRHGR-------RKSLQST 390

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
galene	NP_612084.1	Ion_trans_2	<134..189	CDD:285168	26/54 (48%)
		NESP55	341..586	CDD:115071
		Ion_trans	<621..709	CDD:278921
		Ion_trans_2	626..706	CDD:285168
unc-58	NP_001360793.1	Ion_trans_2	<299..355	CDD:369572	26/55 (47%)
unc-58	NP_001360793.1	Ion_trans_2	435..498	CDD:369572
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010