Protein Alignment galene and twk-16

DIOPT Version :10

• Sequence 1: NP_612084.1
• Gene: galene / 38133
• FlyBaseID: FBgn0035192
• Length: 729
• Species: Drosophila melanogaster
• Sequence 2: NP_508526.2
• Gene: twk-16 / 180594
• WormBaseID: WBGene00006670
• Length: 555
• Species: Caenorhabditis elegans
• Alignment Length: 599
• Identity: 117/599 - (19%)
• Similarity: 179/599 - (29%)
• Gaps: 229/599 - (38%)

  Fly    41 HVLLVLLVVSYCVGGAYLFQHLERPHELEVKRDIQNLRVNLTENIWLLSDDAVVLRESDWMANVS 105
            |..|::||:.|...|.::|..:|.....|:||   |.|:|.|..:      :.:|......::..
 Worm    26 HCSLLMLVLLYSFLGGFIFDRIETNAHAEMKR---NERINRTACV------SQILHSIHRWSHNQ 81

  Fly   106 KHLANFEKQILTAIKADGWDGDEDLRKSQWTFAGSLFYSIIVITTIGYGHISPRTDWGKVTTIFY 170
            .|...:.:.|     ||.::.::| .:|:|.|..:..|...::||:||..|:|.|..|::..|.|
 Worm    82 THKVQYAEDI-----ADCFEPEKD-ERSEWNFVTATLYGFGIVTTLGYNRIAPITYTGRMFCIVY 140

  Fly   171 AIVGIPLMLICLSNIG------------------------------------DVMATS------- 192
            .|.|||:.:|.::|:|                                    .:..||
 Worm   141 GICGIPVTMIIIANVGQYLNNFAGDSRRKIEAYRQQRRMSKASLAGKIYKESSIQVTSLALLCVF 205

  Fly   193 --------------------FRFLYWRICC----------------------YVCTRTA------ 209
                                |..||:...|                      |||...|
 Worm   206 LIYVAVGALLLPLLNGELDFFNGLYFNFLCLTAIDFGQLVPIRVELLPITFLYVCIGLAITTIAI 270

  Fly   210 --------------KRPRNAR-------SRQRSMRSQRHARSQPPPSFRRSMKMTQRSGNDSGLG 253
                          |:.:||.       .:...:|...||                 .|...|:.
 Worm   271 NIGSEYMKKLHYWGKKMKNAAQTRIWFGGKTLKVRDLLHA-----------------VGKKCGVE 318

  Fly   254 PSMGHAYSDPDL-----RTMG----------------RGYDDREFGH-----RSSGGGRNRRQQQ 292
            |.|..|.   ||     ||:.                |....|...|     |.|....:....:
 Worm   319 PGMIDAL---DLENVVERTIAMQEGREPPEDLNDEPPREPSPRSIIHSPCSTRPSNPPMSPPSPR 380

  Fly   293 QQH---LHHD-PRQRHTIYGDGYET-------QTLNRSNRYSSRQRQRDRMRDRHTVERERYSRS 346
            :.|   ...| |..|..:....||.       |.|  ||.:.::..|.....|..|.:.|
 Worm   381 EDHPFIFKMDAPAPRSPLPLPAYELDIKKPIFQAL--SNEFMNQSAQEKLFNDLDTFQIE----- 438

  Fly   347 HLDAGSIEDFGDMQPPAKRAASVRSVRSPHNQES-----SKASRELHRLHSAPGRSRAKSV---- 402
             ::...:||        .:..||..:..|...|.     |....:..|....|.|.|.|..
 Worm   439 -INTELVED--------HKCESVIIIEPPATFEDMTIQHSLCVEDYEREEKVPKRFREKKEMYGR 494

  Fly   403 DPRHVSSHYEDVDEDVVRKTPIIPNRYALDDFGGNRRQAAPRSQSMPRSAHQRQRQKDRERERSP 467
            |||.:   ||...|:..|...:...::     |..|:.....|...|            ||..||
 Worm   495 DPRKL---YETYQEEWDRLERLSDRKH-----GPRRKSVLNLSNCSP------------ERSVSP 539

  Fly   468 QPPPQSSYRQQHDR 481
            .|...|...:.|.|
 Worm   540 SPIRHSLTGEGHRR 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
galene	NP_612084.1	Ion_trans_2	115..189	CDD:462301	25/109 (23%)
		Ion_trans_2	626..706	CDD:462301
twk-16	NP_508526.2	Ion_trans_2	<101..159	CDD:462301	21/57 (37%)