DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment galene and twk-46

DIOPT Version :9

Sequence 1:	NP_612084.1	Gene:	galene / 38133	FlyBaseID:	FBgn0035192	Length:	729	Species:	Drosophila melanogaster
Sequence 2:	NP_741678.1	Gene:	twk-46 / 180252	WormBaseID:	WBGene00006696	Length:	319	Species:	Caenorhabditis elegans

Alignment Length:	144	Identity:	48/144 - (33%)
Similarity:	73/144 - (50%)	Gaps:	23/144 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 LVVSYCVGGAYLFQHLERPHELEVKR----DIQNLRVNLTENIWLLSDDAVVLRESDWMANVSKH 107
            :.|.|...||.:|..:|.|.| :::|    |.||.        |   .|.::..:.| .:.:.|.
Worm    33 VAVVYLFVGAIVFVRIEYPLE-KIEREAYLDYQNQ--------W---RDRLIQLDID-ESEIDKL 84

  Fly   108 LANFEKQILTAIKADGWDGDEDLRKS-QWTFAGSLFYSIIVITTIGYGHISPRTDWGKVTTIFYA 171
            ..|..:..|..|    | .|.:|... .|||..:.|::..:|:|:|||.:||||::||:.||.|.
Worm    85 FLNIREAALNGI----W-MDRNLTSDPNWTFGQAFFFAGTLISTVGYGRVSPRTEYGKLFTILYC 144

  Fly   172 IVGIPLMLICLSNI 185
            ::||||.|..||.|
Worm   145 VIGIPLTLALLSAI 158

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
galene	NP_612084.1	Ion_trans_2	<134..189	CDD:285168	26/52 (50%)
		NESP55	341..586	CDD:115071
		Ion_trans	<621..709	CDD:278921
		Ion_trans_2	626..706	CDD:285168
twk-46	NP_741678.1	Ion_trans_2	<107..164	CDD:285168	26/52 (50%)
twk-46	NP_741678.1	Ion_trans_2	198..274	CDD:285168
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910