Protein Alignment galene and twk-42

DIOPT Version :9

• Sequence 1: NP_612084.1
• Gene: galene / 38133
• FlyBaseID: FBgn0035192
• Length: 729
• Species: Drosophila melanogaster
• Sequence 2: NP_507483.1
• Gene: twk-42 / 180163
• WormBaseID: WBGene00006692
• Length: 444
• Species: Caenorhabditis elegans
• Alignment Length: 686
• Identity: 100/686 - (14%)
• Similarity: 183/686 - (26%)
• Gaps: 398/686 - (58%)

  Fly    41 HVLLVLLVVSYCVGGAYLFQHLERPHELEVKRDIQNLRVNLTENIWLLSDDAVVLRESDWMANVS 105
            |::.:.:::.|...||.||...|..:|..:|.: .|:||..|.    ::...|.::....|.:.:
 Worm    17 HLVKIGVLIVYSFLGAGLFVLCEAENEKSLKHE-DNMRVLRTS----IAAKQVFVQRLQNMYSGN 76

  Fly   106 KHLANFEKQILTAIKAD-----GWDGDEDLRKSQWTFAGSLFYSIIVITTIGYGHISPRTDWGKV 165
            ...:.|.:..|..:.::     |...|..: |::|...|.|:|:..:.||||||.::..|.||::
 Worm    77 GSSSEFSETKLRRVLSEYDAAMGISIDSKM-KTRWDIWGGLYYAGTIYTTIGYGDLAAETIWGRI 140

  Fly   166 TTIFYAIVGIPLMLICLSNIGDVMATSFRFL--YWRICCYVCTRTAKRPRNARSRQRSMRSQRHA 228
            .|:.||::|||:::..|::.|:::   |.|:  :|
 Worm   141 CTMLYAMIGIPIVINILNDWGNML---FYFVDHFW------------------------------ 172

  Fly   229 RSQPPPSFRRSMKMTQRSGNDSGLGPSMGHAYSDPDLRTMGRGYDDREFGHRSSGGGRNRRQQQQ 293
                                                                             
 Worm   173 ----------------------------------------------------------------- 172

  Fly   294 QHLHHDPRQRHTIYGDGYETQTLNRSNRYSSRQRQRDRMRDRHTVERERYSRSHLDAGSIEDFGD 358
                                |.:.|....|.||:.|     |..|:       .|:.|||:
 Worm   173 --------------------QNIGRQWIQSLRQKLR-----RRKVQ-------SLEEGSID---- 201

  Fly   359 MQPPAKRAASVRSVRSPHNQESSKASRELHRLHSAPGRSRAKSVDPRHVSSHYEDVDEDVVRKTP 423
                                                                          |||
 Worm   202 --------------------------------------------------------------KTP 204

  Fly   424 IIPNRYALDDFGGNRRQAAPRSQSMPRSAHQRQRQKDRERERSPQPPPQSSYRQQHDRRAGSLGR 488
            ::
 Worm   205 LM--------------------------------------------------------------- 206

  Fly   489 QSSRYGNHLELPDYDAPPPGRDHRRDRRGHSQGRYEDYVEESFDEGSLYGDNNYEDYPPERHHSR 553
                                                                             
 Worm   207 ----------------------------------------------------------------- 206

  Fly   554 SREPKRNRRRERAERLPPSPRIMSPMGFPVQRQIRRRPSYDYDDDDSMYGDEYGDYGDLLPKDRP 618
                       .....||||:  :|.|                                   .||
 Worm   207 -----------ETSSTPPSPQ--NPNG-----------------------------------TRP 223

  Fly   619 VPIWLCVFLVVSYILGGAVLFAYWENWSFLDSAYFCFITLTTIGFGDFVPAKGVKDESEQSIAYC 683
            :|:.|.:.::..:::.....|||:|||:..:|.||.||::||||||||.|:        .::|..
 Worm   224 IPLLLVLIVLFFWMIQCVAYFAYFENWTLFESVYFFFISMTTIGFGDFTPS--------HTVAVG 280

  Fly   684 SL-YLLFGIALLAMSFNLVQE--EFIANVKEVARRL 716
            .: ::|.|:::::|..|::|.  |||.|  ::.:|:
 Worm   281 GIVFILGGLSVVSMCINVIQMQLEFIFN--QIVQRI 314

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
galene	NP_612084.1	Ion_trans_2	<134..189	CDD:285168	21/54 (39%)
		NESP55	341..586	CDD:115071	13/244 (5%)
		Ion_trans	<621..709	CDD:278921	30/90 (33%)
		Ion_trans_2	626..706	CDD:285168	27/82 (33%)
twk-42	NP_507483.1	Ion_trans_2	<109..165	CDD:285168	21/58 (36%)
		Ion_trans_2	236..304	CDD:285168	26/75 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1418
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810