DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment galene and twk-33

DIOPT Version :9

Sequence 1:	NP_612084.1	Gene:	galene / 38133	FlyBaseID:	FBgn0035192	Length:	729	Species:	Drosophila melanogaster
Sequence 2:	NP_001309463.1	Gene:	twk-33 / 180161	WormBaseID:	WBGene00006685	Length:	617	Species:	Caenorhabditis elegans

Alignment Length:	210	Identity:	52/210 - (24%)
Similarity:	93/210 - (44%)	Gaps:	35/210 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 SLPAHMLEPAKPQRGRCVAAI-CFSWKVLTCIVSHVLLVLLVVSYCVGGAYLFQHLERPHE---- 67
            |.|..|.||..|...|...:: .|::........|..:|:||:.|.:.||.:|..:|..||
Worm   182 SSPGAMGEPVVPTLRRFDKSMYWFAFHRKQIGFRHFSVVILVLLYTLLGAVMFWTVESRHEKAKT 246

  Fly    68 LEVKRDIQNLRVNLTENIWLLSDDAVVLRESDWMANVSKHLANFEKQI------LTAIKADG--- 123
            |:...::::|...|.|||            ::.:.|::......|.::      :..:|.:|
Worm   247 LDHVNNLEHLLDRLAENI------------TESVNNINTTTTEEEMKVYIREAYIELMKLEGQYK 299

  Fly   124 ------WDGDEDLRKSQWTFAGSLFYSIIVITTIGYGHISPRTDWGKVTTIFYAIVGIPLMLICL 182
                  .:.|::.:   |||..:.|:|:.|.||.|||.|:|.:..|:|....|..:.:|:.|:.|
Worm   300 GSTYYKLEADDNWK---WTFESAFFFSMNVYTTTGYGSIAPESTLGQVLVCVYGFIFVPVTLVVL 361

  Fly   183 SNIGDVMATSFRFLY 197
            .::|.........||
Worm   362 RDLGQFFLVHLTKLY 376

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
galene	NP_612084.1	Ion_trans_2	<134..189	CDD:285168	20/54 (37%)
		NESP55	341..586	CDD:115071
		Ion_trans	<621..709	CDD:278921
		Ion_trans_2	626..706	CDD:285168
twk-33	NP_001309463.1	Hid1	<9..141	CDD:301632
		Ion_trans_2	300..368	CDD:285168	21/70 (30%)
		Ion_trans	<404..498	CDD:278921
		Ion_trans_2	407..491	CDD:285168
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1418
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910