DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment galene and egl-23

DIOPT Version :9

Sequence 1:	NP_612084.1	Gene:	galene / 38133	FlyBaseID:	FBgn0035192	Length:	729	Species:	Drosophila melanogaster
Sequence 2:	NP_001255775.1	Gene:	egl-23 / 178358	WormBaseID:	WBGene00001190	Length:	726	Species:	Caenorhabditis elegans

Alignment Length:	256	Identity:	61/256 - (23%)
Similarity:	107/256 - (41%)	Gaps:	86/256 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 KVLTCIVSHVLLVLLVVSYCVGGAYLFQHLE--RPHELEVKRDIQNLRVNLT------------- 82
            |..|.:..|.|:::.|.:|.:.||.:.:.||  ....:|.|.|:....||||
Worm    53 KKATPLFVHFLMIVSVGAYAIFGALVMRSLESRTVTSIEKKTDVHRRHVNLTNFQHPPTPITLEQ 117

  Fly    83 -------ENIWLLSDD------------AVVLRESDWMANVSKHLANFE-------KQILTA--- 118
                   .|...|.|.            |.::|....:.:|.|.:::.|       ::::.|
Worm   118 RHRRRRRHNETALEDHLSEKLSREKRAAAHIMRSRKCVISVIKKMSSMECSFDTLDEKLVKALDE 182

  Fly   119 -----------------------IKADGWDGDEDLRKSQWTFAGSLFYSIIVITTIGYGHISPRT 160
                                   :::.|.:.:||:  |:|:|..||.::..||||||||:::|||
Worm   183 CYHVAVEHNTHVNHVLFTNSKEEVESVGEEAEEDV--SEWSFMDSLLFAFTVITTIGYGNVAPRT 245

  Fly   161 DWGKVTTIFYAIVGIPLMLICLSNIGD------VMATSFRFLYWRICCYVCTRTAKRPRNA 215
            ..|::..|.|.::|||..|:.::::|.      |.|.||           |.:|.|:.:.|
Worm   246 FGGRLFVIGYGLIGIPFTLLAIADLGKFISEMMVEAKSF-----------CRKTWKKLKKA 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
galene	NP_612084.1	Ion_trans_2	<134..189	CDD:285168	23/60 (38%)
		NESP55	341..586	CDD:115071
		Ion_trans	<621..709	CDD:278921
		Ion_trans_2	626..706	CDD:285168
egl-23	NP_001255775.1	Ion_trans_2	216..276	CDD:285168	25/61 (41%)
egl-23	NP_001255775.1	Ion_trans_2	347..423	CDD:285168
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010