| Sequence 1: | NP_612084.1 | Gene: | galene / 38133 | FlyBaseID: | FBgn0035192 | Length: | 729 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001153322.1 | Gene: | Kcnk2 / 16526 | MGIID: | 109366 | Length: | 426 | Species: | Mus musculus |
| Alignment Length: | 188 | Identity: | 59/188 - (31%) |
|---|---|---|---|
| Similarity: | 86/188 - (45%) | Gaps: | 49/188 - (26%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 32 WKVLTCIVSHVLLVLLVVSYCVGGAYLFQHLERPHELEVKRDI---------QNLRVNLTENIWL 87
Fly 88 LSDDAVVLRESDWMANVSKHLANFEKQILTAIKADGWD-GDEDLRKSQWTFAGSLFYSIIVITTI 151
Fly 152 GYGHISPRTDWGKVTTIFYAIVGIPLMLICLSNIGDVMATSF---------RFLYWRI 200 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| galene | NP_612084.1 | Ion_trans_2 | 115..189 | CDD:462301 | 33/74 (45%) |
| Ion_trans_2 | 626..706 | CDD:462301 | |||
| Kcnk2 | NP_001153322.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..36 | ||
| Important for GNG4 binding and L-glutamate release in astrocytes. /evidence=ECO:0000250|UniProtKB:Q920B6 | 17..38 | ||||
| Important for GNG4 binding and L-glutamate release in astrocytes. /evidence=ECO:0000250|UniProtKB:Q920B6 | 51..61 | 1/1 (100%) | |||
| Ion_trans_2 | <138..196 | CDD:462301 | 28/57 (49%) | ||
| Selectivity filter 1. /evidence=ECO:0000250|UniProtKB:Q920B6 | 157..162 | 3/4 (75%) | |||
| Ion_trans_2 | 234..312 | CDD:462301 | |||
| Selectivity filter 2. /evidence=ECO:0000250|UniProtKB:Q920B6 | 266..271 | ||||
| Interaction with AKAP5. /evidence=ECO:0000305|PubMed:17110924 | 298..311 | ||||
| Interaction with AKAP5. /evidence=ECO:0000305|PubMed:17110924 | 313..326 | ||||
| Essential for chloroform and halothane sensitivity. /evidence=ECO:0000269|PubMed:10321245 | 337..385 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||