Protein Alignment galene and galene

DIOPT Version :10

• Sequence 1: NP_612084.1
• Gene: galene / 38133
• FlyBaseID: FBgn0035192
• Length: 729
• Species: Drosophila melanogaster
• Sequence 2: XP_061507114.1
• Gene: galene / 1278512
• VectorBaseID: AGAMI1_010037
• Length: 641
• Species: Anopheles gambiae
• Alignment Length: 760
• Identity: 334/760 - (43%)
• Similarity: 421/760 - (55%)
• Gaps: 159/760 - (20%)

  Fly     1 MSGRRAQSLPAHML---------EPAKPQRGRCVAAICFSWKVLTCIVSHVLLVLLVVSYCVGGA 56
            ||.||....|...|         ||.|..|.:|::.:|..|||.|||.|||.||..||:||..||
Mosquito     1 MSSRRTAPPPMQQLQPQMSISYGEPEKKPRSKCMSFVCCMWKVFTCIFSHVTLVATVVAYCFLGA 65

  Fly    57 YLFQHLERPHELEVKRDIQNLRVNLTENIWLLSDDAVVLRESDWMANVSKHLANFEKQILTAIKA 121
            :.|:|||..:|..||:.|.::|||||:.||.:::|..||.:.:|.:....||.:|||:||||:|.
Mosquito    66 FTFEHLEAENERNVKKGISSIRVNLTDAIWKMTNDRPVLHQQNWTSAAIMHLQSFEKEILTAMKK 130

  Fly   122 DGWDGDEDLRKSQWTFAGSLFYSIIVITTIGYGHISPRTDWGKVTTIFYAIVGIPLMLICLSNIG 186
            |||||:||:.:.||||.|:||||||||||||||||:|:|..||::||||||:||||||:||||||
Mosquito   131 DGWDGNEDVDQIQWTFFGALFYSIIVITTIGYGHIAPKTYMGKISTIFYAILGIPLMLLCLSNIG 195

  Fly   187 DVMATSFRFLYWRICCYVCTRTAKRPRNARSR---------QRSMRSQRHARSQPPPSFRRSMKM 242
            |:||:||||||||:|||||||..||..:.|||         :.||||.:.|.:    :.|||::.
Mosquito   196 DIMASSFRFLYWRVCCYVCTREPKRSNSRRSRSSRGTVRQGRSSMRSVQAAGT----NLRRSVRN 256

  Fly   243 TQRSGNDSGLG----PSMGHAYSDPDLRTMGRGYDDREFGHRSSGGGRNRRQQQQQHLHHDPRQ- 302
            :|||. |||..    |.:.|:|||.|.| .....||..:    ....|:.|||.:    :|.:.
Mosquito   257 SQRSA-DSGFDPYYEPGLSHSYSDTDCR-YNAAMDDAYY----PDNDRSMRQQTK----YDTQNP 311

  Fly   303 ------RHTIYGDGYETQTLNRSNRYSSRQRQRDRMRDRHTVERERYSRSHLDAGSIEDFGDMQP 361
                  ||.|.|.......:|.....||:|.:|                              .|
Mosquito   312 TGPGGIRHQIRGAPNPDAFMNDEYLASSQQIKR------------------------------PP 346

  Fly   362 PAKRAASVRSVRSPHNQESSKASRELHRLHSAPGRSRAKSVDPR--HVSSHYEDVDEDVVRKTPI 424
            |..  :.|.|:....:|.|.:..|:....:..|...||:|:|.|  ...|...|:|:|...||||
Mosquito   347 PGH--SRVESMGLDQSQRSLQKPRQFDGQYRKPQGMRAQSLDRRMFRQGSQMIDMDDDSPCKTPI 409

  Fly   425 IPNRYALDDF---GGNRRQAAPRSQSMPRSAHQRQRQKDRERERSPQPPPQSSYRQQHDRRAGSL 486
            :.|:|||||.   .|...:..|||||||
Mosquito   410 LCNKYALDDVDDQDGRSTRPNPRSQSMP------------------------------------- 437

  Fly   487 GRQSSRYGNHLELPDYDAPPPGRDHRRDRRGHSQGRYEDYVEESFDEGSLYGDNNYEDYPPERHH 551
             ||:.|||:.| :||                    |...|.|          ||...:     :.
Mosquito   438 -RQTGRYGDRL-MPD--------------------RMPYYTE----------DNEIAE-----NM 465

  Fly   552 SRSREPKRNRRRERAERLPPSPRIMSPMGFPVQRQIRRRPSYDYDDDDSMYGDEYGDY-GDLLPK 615
            ...|:....||||......|||||||||||.|.||.|.  ..:..||:|:|.||:..: |:|.|.
Mosquito   466 QSVRKSAPQRRREPRPVPAPSPRIMSPMGFAVHRQARH--LQNVIDDNSLYDDEWDLHSGELPPS 528

  Fly   616 D--RPVPIWLCVFLVVSYILGGAVLFAYWENWSFLDSAYFCFITLTTIGFGDFVPAKGVKDESEQ 678
            .  ||||||||||||||||:.||.:|:.||.|||||||||||||||||||||||||:|||::||.
Mosquito   529 SIVRPVPIWLCVFLVVSYIIAGAFMFSEWEEWSFLDSAYFCFITLTTIGFGDFVPAQGVKNDSEI 593

  Fly   679 SIAYCSLYLLFGIALLAMSFNLVQEEFIANVKEVARRLGILKDDD 723
            |||.||||||||||||||||||||||.|:|||.|||||||||:::
Mosquito   594 SIALCSLYLLFGIALLAMSFNLVQEEVISNVKSVARRLGILKEEE 638

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
galene	NP_612084.1	Ion_trans_2	115..189	CDD:462301	56/73 (77%)
		Ion_trans_2	626..706	CDD:462301	67/79 (85%)
galene	XP_061507114.1	None