DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment galene and Kcnk6

DIOPT Version :9

Sequence 1:	NP_612084.1	Gene:	galene / 38133	FlyBaseID:	FBgn0035192	Length:	729	Species:	Drosophila melanogaster
Sequence 2:	NP_446258.2	Gene:	Kcnk6 / 116491	RGDID:	621450	Length:	313	Species:	Rattus norvegicus

Alignment Length:	150	Identity:	46/150 - (30%)
Similarity:	77/150 - (51%)	Gaps:	25/150 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 LLVLLVVSYC---VGGAYLFQHLERPHELEVKRDIQNLRVNLTENIWLLSDDAVVLRESDWMANV 104
            ||...:|:|.   ..||.|...||||||..::.::..||..|             ||.|..:|
  Rat     6 LLASALVAYAGYLALGALLVARLERPHEARLRAELGTLREQL-------------LRHSPCVA-- 55

  Fly   105 SKHLANFEKQILT------AIKADGWDGDEDLRKSQWTFAGSLFYSIIVITTIGYGHISPRTDWG 163
            :..|..|.:::|.      |:.|:. .|..:.....|.||.:||::..::||:|||:.:|.||.|
  Rat    56 AHALDAFVERVLAAGRLGRAVLANA-SGPANASDPAWDFASALFFASTLVTTVGYGYTTPLTDAG 119

  Fly   164 KVTTIFYAIVGIPLMLICLS 183
            |..:|.:|::|:|:.::.|:
  Rat   120 KAFSIVFALLGVPITMLLLT 139

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
galene	NP_612084.1	Ion_trans_2	<134..189	CDD:285168	20/49 (41%)
		NESP55	341..586	CDD:115071
		Ion_trans	<621..709	CDD:278921
		Ion_trans_2	626..706	CDD:285168
Kcnk6	NP_446258.2	Ion_trans_2	<91..146	CDD:400301	20/48 (42%)
Kcnk6	NP_446258.2	Ion_trans_2	180..259	CDD:400301
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	60	1.000	Domainoid score	I10303
eggNOG	1	0.900	-	-		E1_KOG1418
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	128	1.000	Inparanoid score	I4566
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.860