DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment galene and kcnk2

DIOPT Version :9

Sequence 1:	NP_612084.1	Gene:	galene / 38133	FlyBaseID:	FBgn0035192	Length:	729	Species:	Drosophila melanogaster
Sequence 2:	XP_031758740.1	Gene:	kcnk2 / 100495685	XenbaseID:	XB-GENE-952207	Length:	412	Species:	Xenopus tropicalis

Alignment Length:	183	Identity:	63/183 - (34%)
Similarity:	92/183 - (50%)	Gaps:	27/183 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 AKP-----QRGRCVAAICFSWKVLTCIVSHVLLVLLVVSYCVGGAYLFQHLERPHELEVKRDIQN 76
            |||     :..|.:......||.    ||.|.||  ||.|.:.||.:|:.||:|||     ..|.
Frog    25 AKPAVVSTRDNREITMNVMKWKT----VSTVFLV--VVLYLIIGATVFKALEQPHE-----SAQR 78

  Fly    77 LRVNLTENIWLLSDDAVVLRESDWMANVSKHLANFEKQILTAIKADGWD-GDEDLRKSQWTFAGS 140
            ..:.:.:|.::|:...|.:.|.|.:.          :|::.||.|.... |:...:.|.|....|
Frog    79 TTIVIQKNNFILNHSCVNVTELDELI----------QQLMAAINAGIIPIGNTSHQNSHWDLGSS 133

  Fly   141 LFYSIIVITTIGYGHISPRTDWGKVTTIFYAIVGIPLMLICLSNIGDVMATSF 193
            .|::..||||||:|:|||||..||:..|.||::||||....|:.:||.:.|.|
Frog   134 FFFAGTVITTIGFGNISPRTKGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIF 186

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
galene	NP_612084.1	Ion_trans_2	<134..189	CDD:285168	27/54 (50%)
		NESP55	341..586	CDD:115071
		Ion_trans	<621..709	CDD:278921
		Ion_trans_2	626..706	CDD:285168
kcnk2	XP_031758740.1	Ion_trans_2	<128..182	CDD:400301	27/53 (51%)
kcnk2	XP_031758740.1	Ion_trans_2	220..298	CDD:400301
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910