Protein Alignment galene and kcnk18

DIOPT Version :9

• Sequence 1: NP_612084.1
• Gene: galene / 38133
• FlyBaseID: FBgn0035192
• Length: 729
• Species: Drosophila melanogaster
• Sequence 2: XP_031761959.1
• Gene: kcnk18 / 100486306
• XenbaseID: XB-GENE-6257492
• Length: 429
• Species: Xenopus tropicalis
• Alignment Length: 707
• Identity: 144/707 - (20%)
• Similarity: 220/707 - (31%)
• Gaps: 341/707 - (48%)

  Fly    19 PQRGRCVAAICFSWKVLTCI---VSHVLLVLLVVSYCVGGAYLFQHLERPHELEVKRDIQNLRVN 80
            ||||:|      |||.|...   ..||.||..:|.|.:.||.:|..:|...|.|:.:..:.|
 Frog    28 PQRGKC------SWKCLQAFWISFPHVCLVCSLVLYSILGALMFWFIEGSREKEISQFEEFL--- 83

  Fly    81 LTENIWLL----SDDAVVLRESDWMANVSKHLANFEKQILTAIKADGWDGDEDLRK--SQWTFAG 139
              |.:|::    |.|...:.::.....:.|.||  .:.|:|.::.: |     |:|  .||:|..
 Frog    84 --EKLWMIVQNSSIDNATISDNGSAPEIFKELA--REAIITDLQVE-W-----LQKPEEQWSFKS 138

  Fly   140 SLFYSIIVITTIGYGHISPRTDWGKVTTIFYAIVGIPLMLICLSNIGDVMATSFRFLYWRICCYV 204
            |||:...|.||:|||||.|.|.:||:..:.||.:||||||:.|:::||::|   |.|
 Frog   139 SLFFCCTVFTTVGYGHICPVTMYGKLACMVYATLGIPLMLLLLADLGDILA---RLL-------- 192

  Fly   205 CTRTAKRPRNARSRQRSMRSQRHARSQPPPSFRRSMKMTQRSGNDSGLGPSMGHAYSDPDLRTMG 269
             :||.||...|.::
 Frog   193 -SRTYKRAVLACNK--------------------------------------------------- 205

  Fly   270 RGYDDREFGHRSSGGGRNRRQQQQQHLHHDPRQRHTIYGDGYETQTLNRSNRYSSRQRQRDRMRD 334
                                      |.|.|:
 Frog   206 --------------------------LCHKPK--------------------------------- 211

  Fly   335 RHTVERERYSRSHLDAGSIEDFGDMQPPAKRAASVRSVRSPHNQESSKASRELHRLHSAPGRSRA 399
                                       |.|.::                   ||:.||..
 Frog   212 ---------------------------PIKLSS-------------------LHKEHSGK----- 225

  Fly   400 KSVDPRHVSSHYEDVDEDVVRKTPIIPNRYALDDFGGNRRQAAPRSQSMPRSAHQRQRQKDRE-- 462
                    ||..:.:|..|..|.|:            |..:......|:.|...|.:.....|
 Frog   226 --------SSLLKTMDSRVSMKEPL------------NITEVIKTQASVKRKYLQMRNIDIFELI 270

  Fly   463 --RERSPQPPPQSSYRQQHDRRAGSLGRQSSRYGNHLELPDYDAPPPGRDHRRDRRGHSQGRYED 525
              :|.....|.:||.:|:                 ....||.|..||                .|
 Frog   271 IVKENQKVLPLKSSLQQK-----------------SFSCPDLDLWPP----------------SD 302

  Fly   526 YVEESFDEGSLYGDNNYEDYPPERHHSRSREPKRNRRRERAERLPPSPRIMSPMGFPVQRQIRRR 590
            ...::||:
 Frog   303 SAMQNFDK--------------------------------------------------------- 310

  Fly   591 PSYDYDDDDSMYGDEYGDYGDLLPKDRPVPIWLCVFLVVSYILGGAVLFAYWE-NWSFLDSAYFC 654
                       .|:|. |:.|       |||.|.|.::|:||:.||.:...|| :|:.:|:.|||
 Frog   311 -----------IGEEL-DHLD-------VPIVLIVLVMVAYIMCGACILPLWEDDWTTIDAFYFC 356

  Fly   655 FITLTTIGFGDFVPAKGVKDESEQSIAYCSLYLLFGIALLAMSFNLVQEEFIANVKE 711
            |:|||||||||.:|      :........|.|.:.|:.::.|:|.|.|...::..|:
 Frog   357 FVTLTTIGFGDIIP------KHPNYFLLLSAYTVVGMVIVCMAFKLGQNRLVSFYKQ 407

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
galene	NP_612084.1	Ion_trans_2	<134..189	CDD:285168	29/54 (54%)
		NESP55	341..586	CDD:115071	30/248 (12%)
		Ion_trans	<621..709	CDD:278921	33/88 (38%)
		Ion_trans_2	626..706	CDD:285168	30/80 (38%)
kcnk18	XP_031761959.1	Ion_trans_2	<131..>175	CDD:400301	21/43 (49%)
		Ion_trans_2	327..402	CDD:400301	30/80 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	173	1.000	Inparanoid score	I3972
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D542195at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11003
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2863
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.160