DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment galene and kcnk7

DIOPT Version :9

Sequence 1:	NP_612084.1	Gene:	galene / 38133	FlyBaseID:	FBgn0035192	Length:	729	Species:	Drosophila melanogaster
Sequence 2:	NP_001116288.1	Gene:	kcnk7 / 100144289	XenbaseID:	XB-GENE-5731928	Length:	322	Species:	Xenopus tropicalis

Alignment Length:	197	Identity:	53/197 - (26%)
Similarity:	90/197 - (45%)	Gaps:	50/197 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 VLLVLLVVSYCVG---GAYLFQHLERPHELEVKRDIQNLRVNLTENIWLLSDDAVVLRESDWMAN 103
            :.|:||::||.:.   ||::|..||:|.|..::|:::.:                      |...
Frog     7 LFLLLLLLSYSLFLLLGAFVFSTLEQPQEERLRREVETM----------------------WSEF 49

  Fly   104 VSKH-------LANFEKQILTAIKADGWDGDED--LRKSQWTFAGSLFYSIIVITTIGYGHISPR 159
            ::||       |.:|.::.| .:|:.|.....:  :.:.:|.|..|||::...:|||||||..|.
Frog    50 LAKHPCLSEVLLDDFIRKAL-LVKSFGVSVHRNISIHELKWDFISSLFFTGTTLTTIGYGHPFPI 113

  Fly   160 TDWGKVTTIFYAIVGIPLMLICLSNIGDVMATSFRFLYWRICCYVCTRTAKRPRNARSRQRSMRS 224
            :..||...:.|||.||||.|..||    ::..:...|.|           .:|.|...||.|:..
Frog   114 SLGGKAFCLVYAIFGIPLTLSVLS----IIVRNLLILLW-----------DKPINKLQRQCSISR 163

  Fly   225 QR 226
            ::
Frog   164 KK 165

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
galene	NP_612084.1	Ion_trans_2	<134..189	CDD:285168	25/54 (46%)
		NESP55	341..586	CDD:115071
		Ion_trans	<621..709	CDD:278921
		Ion_trans_2	626..706	CDD:285168
kcnk7	NP_001116288.1	Ion_trans_2	<88..141	CDD:285168	25/56 (45%)
kcnk7	NP_001116288.1	Ion_trans_2	178..254	CDD:285168
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910