Protein Alignment mwh and Frl

DIOPT Version :9

• Sequence 1: NP_001261244.1
• Gene: mwh / 38131
• FlyBaseID: FBgn0264272
• Length: 1069
• Species: Drosophila melanogaster
• Sequence 2: NP_729954.2
• Gene: Frl / 39561
• FlyBaseID: FBgn0267795
• Length: 1183
• Species: Drosophila melanogaster
• Alignment Length: 915
• Identity: 170/915 - (18%)
• Similarity: 283/915 - (30%)
• Gaps: 336/915 - (36%)

  Fly   273 NGSLAS---------YKIGGSEQ-SWPQAPVYSKENQRP-PVYNPEDYVHSLRKFIKASGS---- 322
            |||::|         |.||.|.| ...:.|.....:|:| |..:..|     |:|.|...|
  Fly    39 NGSISSGTLQKQDLRYDIGCSSQYQHVRQPSLRSRSQQPMPTTDELD-----RRFAKVLASMDLP 98

  Fly   323 ---AKKLSIYDVFTGPSPK-----EEASRSATLPAKHSEYKSPIPAPPENDREMSLRQF------ 373
               ||.|..||    ...|     ::....|..|..|...|......|:..|...|..|
  Fly    99 PDKAKLLRNYD----DEKKWDMICDQEMVQAKDPPSHYLSKLRTYLDPKASRSHRLYLFYFLCQK 159

  Fly   374 ------GSITDLLTKLRADLRVSFPSFVQEFVGTPADGISHL-------LEVLRAIQMAQA---- 421
                  .:.|.:|..|...||.:...:|:||:.....|:..|       |:::|..|..|.
  Fly   160 RKMVGESTSTQVLRDLEISLRTNHIEWVKEFLDDTNQGLDALVDYLSFRLQMMRHEQRLQGVLCA 224

  Fly   422 ------------------SNAPAPMPGASSSLAMNRN---------------------------- 440
                              .|:.:..||....|..:.|
  Fly   225 SEERLNLTNGGDGGEIVMGNSSSVSPGGGGGLLSHGNSTGHGLANGTLDSRQQHTMSYGFLRPTI 289

  Fly   441 -----PQSYQRR----------ALLDELSCLQCLSICCSRSLDAIARLGNTPVG----------L 480
                 ..|.:||          |..|::.    :||.|.|:      :.|...|          :
  Fly   290 ADALDSPSLKRRSRHIAKLNMGAATDDIH----VSIMCLRA------IMNNKYGFNMVIQHREAI 344

  Fly   481 MPLASSATGQGIRARILALQLLASACDRQPFGSGSGGQKIASAGHTAVSDAMSTLRLRCSEPVRF 545
            ..:|.|...:.:|.:.|.|:|||:.|             :...||..:..:....:..|.|..||
  Fly   345 NCIALSLIHKSLRTKALVLELLAAIC-------------LVKGGHEIILGSFDNFKDVCQEKRRF 396

  Fly   546 RLLVG-ILNSGGGSGELQCAGVKFLNTFIESAVSIQQRLYIQAELFQAGLDASTLARTISSSSPW 609
            :.|:. .:|....:.:...|.::|:|..:.|...:..|:::|.|....|||            .:
  Fly   397 QTLMEYFMNFEAFNIDFMVACMQFMNIVVHSVEDMNYRVHLQYEFTALGLD------------KY 449

  Fly   610 LDALKIEVKRFNELHIDVDQMITRARDAERVRSQMVILERRVQILHEEKAVLTSMERRLQERCAE 674
            |:  :|.:....||.:.:...:....|              |..|.|:....||...|:||...:
  Fly   450 LE--RIRLTESEELKVQISAYLDNVFD--------------VAALMEDSETKTSALERVQELEDQ 498

  Fly   675 LQREIFRLQGTQQQSKFKPVESSHQPVALPRQVPPPKKNKQNSSEHEDEGISSSETGASLSPVPI 739
            |:|||.|      .|:|                      ....:|.|.|.::
  Fly   499 LEREIDR------NSEF----------------------LYKYAELESESLT------------- 522

  Fly   740 LILPSKAKPSRKVVEEDEDDAATIEDVIEE----LDNIVSEAEKQISSQTSSVTRPKMRHHRPVE 800
                         ::.:.:..|.|...:||    :..::...|:::..      |..:.|.:.:|
  Fly   523 -------------LKTEREQLAMIRQKLEEELTVMQRMLQHNEQELKK------RDTLLHTKNME 568

  Fly   801 KEIVPVNIVPQPPRKSRSLAHLVPRTDCSDQEGS--DYGMVLHQPADPDAAERLAAMQSFFDEVD 863
            .:.:           ||||    ||: .|..:||  :.|::
  Fly   569 LQTL-----------SRSL----PRS-ASSGDGSLANGGLM------------------------ 593

  Fly   864 YDAPETDQPAAYQMESPTPDMPEANATATAYNASTNRELLDVIMNARHDDHDPTMQALRKSVQDA 928
              |..|...|:..:..|.|.|| |:.||:               :|......|............
  Fly   594 --AGSTSGAASLTLPPPPPPMP-ASPTAS---------------SAAPPPPPPPAPPAPPPPPGF 640

  Fly   929 APVTIPHHPVKVKAPAPP----------PPTPPAQQF----NGVFFMTGMNTPQKYPKPDIS-AA 978
            :|:..|...:...||:||          ||.||...|    :|...:. ...|.||..|.:: .|
  Fly   641 SPLGSPSGSLASTAPSPPHAPPMLSSFQPPPPPVAGFMPAPDGAMTIK-RKVPTKYKLPTLNWIA 704

  Fly   979 LQARRVTKNV---------------ERLEAAFASAHPEALNEAAIGRE---KSRSNQQIYFTSNL 1025
            |:..:|...:               ...|..|......||...:.|.|   ..:|:::.....|:
  Fly   705 LKPNQVRGTIFNELDDEKIFKQIDFNEFEERFKIGIGGALRNGSNGTEVDGSLQSSKRFKRPDNV 769

  Fly  1026 AMRMH 1030
            ::..|
  Fly   770 SLLEH 774

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mwh	NP_001261244.1	Drf_GBD	<380..506	CDD:283920	37/207 (18%)
		Drf_FH3	524..725	CDD:283917	41/201 (20%)
Frl	NP_729954.2	Drf_GBD	77..371	CDD:283920	60/325 (18%)
		Drf_FH3	374..567	CDD:283917	48/280 (17%)
		FH2	687..1063	CDD:280362	16/89 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1923
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3972
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR45857
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.860