Protein Alignment mwh and fmnl1b

DIOPT Version :9

• Sequence 1: NP_001261244.1
• Gene: mwh / 38131
• FlyBaseID: FBgn0264272
• Length: 1069
• Species: Drosophila melanogaster
• Sequence 2: XP_009295890.3
• Gene: fmnl1b / 100536330
• ZFINID: ZDB-GENE-130306-1
• Length: 1026
• Species: Danio rerio
• Alignment Length: 846
• Identity: 169/846 - (19%)
• Similarity: 282/846 - (33%)
• Gaps: 260/846 - (30%)

  Fly   232 LEMAPSVCE----MAGQGQSGPVPPQKASGSNSS-KGTNKCGASSLN------GSLASYKIGGSE 285
            |||:| |.|    ::..||..|..|:....|... :.......:|:|      ..|:.|   .||
Zfish     8 LEMSP-VREIKRPLSTYGQKPPAAPKLPQPSEEELEERFSIVLNSMNLPPDKVMLLSQY---DSE 68

  Fly   286 QSWPQAPVYSKENQRPPVYNPED-YVHSLRKFIKASGSAKKLSIYDVFTGPSPKEEASRSATLPA 349
            :.|...    .:.:|..|.||.. |:..|:..::..|..|
Zfish    69 KKWELV----CDQERFQVKNPPSAYIQKLKSVLEQGGGRK------------------------- 104

  Fly   350 KHSEYKSPIPAPPENDREMSLRQFGSITDLLTKLRADLRVSFPSFVQEFVGTPADGISHLLEVLR 414
                :|               |:....|.:|.:|...||.:...:.:||:....:|:..|::.|.
Zfish   105 ----FK---------------RRVQESTQVLRELEISLRTNHIGWAEEFLNEENNGLDVLVDYLS 150

  Fly   415 AIQMA------------------------QASNAPAPMPGASSSLAMNRNPQSYQRRALLDELSC 455
            ..|.|                        .|:|:|......|:.....|....|.|  :|.:.:.
Zfish   151 FAQRAVIYDMDSSSENGSFEEKSVEDLTTSATNSPTHNSPRSARPFTTRKALRYSR--MLSQNNH 213

  Fly   456 LQCLSICCSRSLDAIARLGNTPVGLMP-----LASSATGQGIRARILALQLLASACDRQPFGSGS 515
            |. |.|.|.|:: ...:||...|...|     :..|...:..|.:.|.|:|||:.|
Zfish   214 LH-LCIMCLRAI-MNYQLGFNQVTAHPSCVNEITLSLNNRSARTKALVLELLAAVC--------- 267

  Fly   516 GGQKIASAGHTAVSDAMSTLRLRCSEPVRFRLLVGILNSGGGSGELQCAGVKFLNTFIESAVSIQ 580
                :...||..:..|.:..|..|.|..||..|:....:...:.:...|.::|:|..:.|...:.
Zfish   268 ----LVRGGHEMILAAFNNFREVCGEKNRFEKLMEYFRNEESNIDFMVACMQFINIVVHSVEDMN 328

  Fly   581 QRLYIQAELFQAGLDASTLARTISSSSPWLDALKIEVKRFNELHIDVDQMITRARDAERVRSQMV 645
            .|:::|.|..|.|||:......::.|    :.|:|:::.:.:...||..|:   .|||...:.|.
Zfish   329 FRVFLQYEFTQLGLDSYLEKLNMTES----ERLQIQIQAYLDNVFDVGAML---EDAEAKNTLME 386

  Fly   646 ILERRVQILHEEKAVLTSMERRLQERCAELQREIFRLQGT---QQQSKFKPVESSHQPVALPRQV 707
            .||.    |.|:.   |.:..||.      |.||..|:.|   :||.    ::||.|...|...|
Zfish   387 HLEE----LQEQN---TQLNTRLH------QCEIEALEKTTDLEQQL----IQSSKQVELLKESV 434

  Fly   708 PPPKKNKQNSSEHEDEGISSSETGASLSPVPILILPSKAKPSRKVVEEDEDDAATIEDVIEELDN 772
                         ::..:|||...:           |..:..|:.|..:
Zfish   435 -------------KEVRLSSSSFSS-----------SSRRTDRRAVRPN---------------- 459

  Fly   773 IVSEAEKQISSQTSSVTRPKMRHHR---PVEKEIVPVNIVPQPPRKSRSLA-----HLVPRTDCS 829
                     |:.|.:.:|.:.|..|   .||:.::         |..||.:     |::...:.:
Zfish   460 ---------STHTQTDSRRRCRWRRCQLLVERGLI---------RMERSASGALDLHIIAAANTT 506

  Fly   830 DQEGSDYGMVLHQPADPDAAERLAAMQSFFDEVDYDAPETDQPAAYQMESPTPDMPEANATATA- 893
            |:...:...|...|..|..                .||....|......:| |..|....|.|.
Zfish   507 DKCSKETSPVPQSPPPPPV----------------PAPPPPPPPPPLALAP-PTSPFIGRTGTIK 554

  Fly   894 -------------------YNASTNRELLDVIMNARHDD------HDPTMQALRKSVQDAAPVTI 933
                               :.|....::...:.....|.      :....:.|.|:...:|||.:
Zfish   555 TGVKGKQPIKTKYRMPLLNWQALMEEQVAGTVFTELDDQTVLQELNMDVFEELFKTKAQSAPVDV 619

  Fly   934 PHHPVKV--KAPAPPPPTPPAQQFNGVFFM--TGMNTPQKYPKPDISAALQARRVTKNVERLEAA 994
            ....|||  ||.:......|.:..|....:  .||:|.|      |..|:|    |.|:|.|::.
Zfish   620 GTLKVKVAQKASSKISLLEPNRAKNLAITLRKAGMSTAQ------ICTAIQ----TYNLELLKSD 674

  Fly   995 F 995
            |
Zfish   675 F 675

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mwh	NP_001261244.1	Drf_GBD	<380..506	CDD:283920	35/154 (23%)
		Drf_FH3	524..725	CDD:283917	49/203 (24%)
fmnl1b	XP_009295890.3	Drf_GBD	33..268	CDD:310750	55/302 (18%)
		Drf_FH3	271..437	CDD:310747	49/202 (24%)
		FH2	559..925	CDD:280362	26/127 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910