DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment LysD and SPACA3

DIOPT Version :9

Sequence 1:	NP_476823.1	Gene:	LysD / 38127	FlyBaseID:	FBgn0004427	Length:	140	Species:	Drosophila melanogaster
Sequence 2:	NP_776246.1	Gene:	SPACA3 / 124912	HGNCID:	16260	Length:	215	Species:	Homo sapiens

Alignment Length:	156	Identity:	50/156 - (32%)
Similarity:	73/156 - (46%)	Gaps:	28/156 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 AFIVLVALAC---------AAPAFGRTMDRCSLAREMSNLGVPRDQ---LARWACIAEHESSYRT 55
            |.|:|:||.|         .|..:|    ||.|||.:.:.|:...:   ||.|.|:|...|.:..
Human    67 AGIMLLALVCLLSCLLPSSEAKLYG----RCELARVLHDFGLDGYRGYSLADWVCLAYFTSGFNA 127

  Fly    56 GVVGPENYNGSNDYGIFQINDYYWCAPPSGRFSYNECGLSCNALLTDDITHSVRCAQKVLSQ-QG 119
            ..:..| .:||.:.||||||...||:..:.... |.|.:.|:.||..::..:|.||.|:..: ||
Human   128 AALDYE-ADGSTNNGIFQINSRRWCSNLTPNVP-NVCRMYCSDLLNPNLKDTVICAMKITQEPQG 190

  Fly   120 WSAWSTW-HYCSG-----WLPSIDDC 139
            ...|..| |:|.|     |   :|.|
Human   191 LGYWEAWRHHCQGKDLTEW---VDGC 213

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LysD	NP_476823.1	LYZ_C_invert	19..139	CDD:381618	41/129 (32%)
SPACA3	NP_776246.1	LYZ_C	88..213	CDD:340383	42/133 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153962
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2BPI7
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1551203at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8437
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11407
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X173
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.850