Protein Alignment Trh and Hn

DIOPT Version :9

• Sequence 1: NP_612080.1
• Gene: Trh / 38121
• FlyBaseID: FBgn0035187
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_001261542.1
• Gene: Hn / 38871
• FlyBaseID: FBgn0001208
• Length: 452
• Species: Drosophila melanogaster
• Alignment Length: 420
• Identity: 212/420 - (50%)
• Similarity: 282/420 - (67%)
• Gaps: 16/420 - (3%)

  Fly    90 GNLARALQVFQELGINVLHLELSPLEMATNQADVLVDVECDQRRLDQVVKMLNREVASVNYTSVN 154
            |.||..|.:|::..||::|:| |...:.....:..|:.:.....|.:.::.:..:.:..|..|.:
  Fly    46 GALANILAIFKKHDINLVHIE-SRSSLRVPGYEFFVEADGKSGALGKAIEDVKEQCSYFNIISRD 109

  Fly   155 TQGLARAPSLSACSSFDFGDMVWFPRKISDLDK-AQNVLMYGSELDADHPGFKDPVYRKRREQFS 218
            .:..|.|             :.||||:|.|||: |..:|.||||||||||||.||.|||||:.|:
  Fly   110 YKDNATA-------------VPWFPRRIRDLDRFANQILSYGSELDADHPGFTDPEYRKRRKYFA 161

  Fly   219 AIANNFKHGNPIPRVQYTPEEVKTWGTVFLELHRLYVLHAVPEYMDNWPELEKYCGYREDNVPQL 283
            .||.|:|||.|:|.|.||.||::|||.:|..|.:||..||..||...:|.|...||:||||:|||
  Fly   162 DIAYNYKHGEPLPHVDYTKEEIETWGIIFRNLTKLYKTHACREYNHVFPLLVDNCGFREDNIPQL 226

  Fly   284 QDVSVYLKRKTGFQLRPVAGYLSPRDFLSGLAFRVFHCTQYIRHSSDPFYTPEPDCCHELLGHMP 348
            :|||.:|:..|||.||||||.||.||||:||||||||.||||||.|.|.||||||.||||:||:|
  Fly   227 EDVSNFLRDCTGFTLRPVAGLLSSRDFLAGLAFRVFHSTQYIRHPSKPMYTPEPDVCHELMGHVP 291

  Fly   349 LLANSSFAQFSQEIGLASLGASDADIEKLATLYFFTVEFGLCKQADSTFKVYGAGLLSSVAELQH 413
            |.|:.:|||||||||||||||.|..||||:|:::||||:|:|:| :...|.||||||||..||::
  Fly   292 LFADPAFAQFSQEIGLASLGAPDDYIEKLSTIFWFTVEYGVCRQ-EGELKAYGAGLLSSYGELEY 355

  Fly   414 AITAENKIKKFDPEVTCQQECIITSYQNAYYYTDSFEEAKEQMRAFAESIQRPFGVRYNPYTMSV 478
            .:|.:.::|.|:||||...:..||.:|..||..||||.|||:...||.||.||||||||.||.||
  Fly   356 CLTDKPQLKDFEPEVTGVTKYPITQFQPLYYVADSFETAKEKTIKFANSIPRPFGVRYNAYTQSV 420

  Fly   479 EVLSNAKKITAVVSELRGDLSIVCSALRKI 508
            |||.:..:|:.::..:..:..|:.:|:.|:
  Fly   421 EVLDSKPQISNLMDNINSEFQILQNAVAKL 450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trh	NP_612080.1	Trp_5_monoox	34..509	CDD:130337	212/420 (50%)
		ACT_TPH	79..152	CDD:153201	13/61 (21%)
		Biopterin_H	177..506	CDD:278766	195/329 (59%)
Hn	NP_001261542.1	Phe4hydrox_tetr	15..451	CDD:130335	212/420 (50%)
		ACT_AAAH	32..107	CDD:153176	13/61 (21%)
		Biopterin_H	118..447	CDD:278766	194/329 (59%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449664
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3186
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000587
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100921
Panther	1	1.100	-	-	P	PTHR11473
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.740