Protein Alignment Trh and th

DIOPT Version :9

• Sequence 1: NP_612080.1
• Gene: Trh / 38121
• FlyBaseID: FBgn0035187
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_571224.1
• Gene: th / 30384
• ZFINID: ZDB-GENE-990621-5
• Length: 489
• Species: Danio rerio
• Alignment Length: 447
• Identity: 215/447 - (48%)
• Similarity: 285/447 - (63%)
• Gaps: 32/447 - (7%)

  Fly    72 QHSPGER-ISIIFTLR-NQVGNLARALQVFQELGINVLHLELSPLEMATNQADVLVD----VECD 130
            :.|.|:. ||:.|||| ::...|:|.|:||:.....:.|||..|   :....|.|.|    |:|:
Zfish    66 EESDGKALISLFFTLRCSKSPALSRTLKVFETFEAKIHHLETRP---SRKPKDGLEDLEYYVQCE 127

  Fly   131 QRRLD--QVVKMLNREVASVNYTSVNTQGLARAPSLSACSSFDFGDMVWFPRKISDLDKAQN-VL 192
            ....|  .:|..|.|....|..|                ....|.   ||||||::|||..: |.
Zfish   128 VHLSDVSTLVSSLKRSAEDVKTT----------------KEVKFH---WFPRKIAELDKCHHLVT 173

  Fly   193 MYGSELDADHPGFKDPVYRKRREQFSAIANNFKHGNPIPRVQYTPEEVKTWGTVFLELHRLYVLH 257
            .|..:||.|||||.||||||||:....||..::||.|||||.||.||:.||..|:..|..||..|
Zfish   174 KYDPDLDQDHPGFTDPVYRKRRKMIGDIAFKYRHGEPIPRVDYTEEEIGTWREVYSTLRDLYTTH 238

  Fly   258 AVPEYMDNWPELEKYCGYREDNVPQLQDVSVYLKRKTGFQLRPVAGYLSPRDFLSGLAFRVFHCT 322
            |..|:::.:..|||:|||..||:|||:|||.:||.:||||||||||.||.||||:.||||||.||
Zfish   239 ACSEHLEAFRLLEKHCGYSPDNIPQLEDVSCFLKERTGFQLRPVAGLLSARDFLASLAFRVFQCT 303

  Fly   323 QYIRHSSDPFYTPEPDCCHELLGHMPLLANSSFAQFSQEIGLASLGASDADIEKLATLYFFTVEF 387
            |||||:|.|.::|||||.||||||:|:|::.:||||||.||||||||||.|||||:|:|:|||||
Zfish   304 QYIRHASSPMHSPEPDCVHELLGHVPILSDRTFAQFSQSIGLASLGASDEDIEKLSTMYWFTVEF 368

  Fly   388 GLCKQADSTFKVYGAGLLSSVAELQHAITAENKIKKFDPEVTCQQECIITSYQNAYYYTDSFEEA 452
            |||||. ...|.||||||||..||.|:::.|.:.::|||::...|.....:||..|:.::||.:|
Zfish   369 GLCKQG-GVIKAYGAGLLSSYGELVHSLSDEPERREFDPDIVAVQPYQDQTYQPVYFVSESFVDA 432

  Fly   453 KEQMRAFAESIQRPFGVRYNPYTMSVEVLSNAKKITAVVSELRGDLSIVCSALRKIS 509
            .|::|.:...|:|||.||::|||.|:|||.|..||...:..::.:|.|:..||..::
Zfish   433 TEKLRTYVTRIKRPFSVRFDPYTDSIEVLDNPLKIQKGLETIKDELKILTDALNVLA 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trh	NP_612080.1	Trp_5_monoox	34..509	CDD:130337	215/445 (48%)
		ACT_TPH	79..152	CDD:153201	25/79 (32%)
		Biopterin_H	177..506	CDD:278766	185/329 (56%)
th	NP_571224.1	Tyr_3_monoox	36..489	CDD:130336	215/445 (48%)
		ACT	36..151	CDD:298841	28/103 (27%)
		Biopterin_H	157..486	CDD:278766	185/329 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3186
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D361696at33208
OrthoFinder	1	1.000	-	-		FOG0000587
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.820