Protein Alignment Trhn and Tph1

DIOPT Version :10

• Sequence 1: NP_612080.1
• Gene: Trhn / 38121
• FlyBaseID: FBgn0035187
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_001094104.1
• Gene: Tph1 / 24848
• RGDID: 3895
• Length: 444
• Species: Rattus norvegicus
• Alignment Length: 458
• Identity: 256/458 - (55%)
• Similarity: 345/458 - (75%)
• Gaps: 36/458 - (7%)

  Fly    67 QDN--GRQHSPGE-RISIIFTLRNQVGNLARALQVFQELGINVLHLELSPLEMATNQADVLVDVE 128
            :||  .:.||... |:::||:|:|:||.|.:||::|||..:|:||:|....:...::.::.||.:
  Rat     3 EDNKENKDHSSERGRVTLIFSLKNEVGGLIKALKIFQENHVNLLHIESRKSKRRNSEFEIFVDCD 67

  Fly   129 CDQRRLDQVVKMLNREVASVNYTSVNTQGLARAPSLSACSSFDFGDMV-----------WFPRKI 182
            .::.:|:.:..:|.      ::|:|              .|.|..|.:           |||:||
  Rat    68 INREQLNDIFPLLK------SHTTV--------------LSVDSPDQLPEKEDVMETVPWFPKKI 112

  Fly   183 SDLDKAQN-VLMYGSELDADHPGFKDPVYRKRREQFSAIANNFKHGNPIPRVQYTPEEVKTWGTV 246
            ||||...| ||:||||||||||||||.|||:||:.|:.:|.|:|||:|||::::|.||:|||||:
  Rat   113 SDLDFCANRVLLYGSELDADHPGFKDNVYRRRRKYFAELAMNYKHGDPIPKIEFTEEEIKTWGTI 177

  Fly   247 FLELHRLYVLHAVPEYMDNWPELEKYCGYREDNVPQLQDVSVYLKRKTGFQLRPVAGYLSPRDFL 311
            |.||::||..||..||:.|.|.|.|||||||||||||:|||.:||.:|||.:|||||||||||||
  Rat   178 FRELNKLYPTHACREYLRNLPLLSKYCGYREDNVPQLEDVSNFLKERTGFSIRPVAGYLSPRDFL 242

  Fly   312 SGLAFRVFHCTQYIRHSSDPFYTPEPDCCHELLGHMPLLANSSFAQFSQEIGLASLGASDADIEK 376
            |||||||||||||:||||||.||||||.|||||||:||||..|||||||||||||||||:..::|
  Rat   243 SGLAFRVFHCTQYVRHSSDPLYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGASEETVQK 307

  Fly   377 LATLYFFTVEFGLCKQADSTFKVYGAGLLSSVAELQHAITAENKIKKFDPEVTCQQECIITSYQN 441
            |||.|||||||||||| |...:|:|||||||::||:||::...|:|.|||:|.|:|||:|||:|:
  Rat   308 LATCYFFTVEFGLCKQ-DGQLRVFGAGLLSSISELRHALSGHAKVKPFDPKVACKQECLITSFQD 371

  Fly   442 AYYYTDSFEEAKEQMRAFAESIQRPFGVRYNPYTMSVEVLSNAKKITAVVSELRGDLSIVCSALR 506
            .|:.::|||:|||:||.||::::|||||:|||||.|::||.::|.||:.::|||.||.:|..||.
  Rat   372 VYFVSESFEDAKEKMREFAKTVKRPFGVKYNPYTQSIQVLRDSKSITSAMNELRHDLDVVNDALA 436

  Fly   507 KIS 509
            ::|
  Rat   437 RVS 439

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trhn	NP_612080.1	Trp_5_monoox	34..509	CDD:130337	255/456 (56%)
Tph1	NP_001094104.1	Trp_5_monoox	3..439	CDD:130337	255/456 (56%)