DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bab1 and nacc1

DIOPT Version :9

Sequence 1:	NP_728565.1	Gene:	bab1 / 38116	FlyBaseID:	FBgn0004870	Length:	977	Species:	Drosophila melanogaster
Sequence 2:	NP_001184134.2	Gene:	nacc1 / 733749	XenbaseID:	XB-GENE-979467	Length:	495	Species:	Xenopus tropicalis

Alignment Length:	318	Identity:	73/318 - (22%)
Similarity:	119/318 - (37%)	Gaps:	109/318 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   113 LTTIFDQLLQNECFVDVTLACDGRSMKAHKMVLSACSPYFQTLLAETPCQHPIV-IMRDVNWSDL 176
            |..:.:|.||. .:.||::...|...|||:.||:|.|.||:.|...:  ::|:| :...|.....
Frog    17 LECLNEQRLQG-LYCDVSVVVRGHQFKAHRAVLAASSSYFRDLFHSS--KNPVVELPGSVQPQSF 78

  Fly   177 KAIVEFMYRGEINVS-QDQI-----GPLLRIAEM--------LKV-------RGLADVTHME--- 217
            :.|:.|.|.|.:::: .||.     ...|:|.|:        |||       :||    |.|
Frog    79 QQILSFCYTGRLSMNVGDQFLLMYTAGFLQIQEIMEKGTEFFLKVSSPSCDSQGL----HPEETP 139

  Fly   218 -------AATAAAAAASSERMPSSPKESTSTSRTEHDREREAEELLAFMQPEKKLRTSDWDPAEL 275
                   |||.||||.::..:.||   |:|:||.                  .|::|...:...:
Frog   140 GSEPPSPAATVAAAATAAAALASS---SSSSSRA------------------PKVKTESQESEAV 183

  Fly   276 RLSPLERQQGRNVRKRRWPSADTIFNPPAPPSPLSSLIAAERMELEQKERERQRDCSLMTPPPKP 340
            :.:|        |.||.|                         |..|||..     .:....|:.
Frog   184 QCTP--------VAKRLW-------------------------EGGQKEAG-----GVGRKVPRF 210

  Fly   341 PMSSGSTVGATRRLETAIHALDMPSPAATPGPLS--RSSRP---HSQSPQQQQAQQQG 393
            ....|:.||...::..|      .|...:||..|  .|..|   |::..::::..:.|
Frog   211 SQGGGAAVGPAGQVAPA------GSERTSPGTSSAYTSDSPGSYHNEEDEEEEVGEDG 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bab1	NP_728565.1	BTB	117..216	CDD:279045	33/120 (28%)
		BTB	128..213	CDD:197585	30/106 (28%)
		HTH_psq	569..614	CDD:283007
nacc1	NP_001184134.2	BTB_POZ_BTBD14B_NAC1	3..125	CDD:349599	32/110 (29%)
nacc1	NP_001184134.2	BEN	366..444	CDD:214981
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I5158
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050