DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bab1 and CG32121

DIOPT Version :9

Sequence 1:	NP_728565.1	Gene:	bab1 / 38116	FlyBaseID:	FBgn0004870	Length:	977	Species:	Drosophila melanogaster
Sequence 2:	NP_001097599.1	Gene:	CG32121 / 317867	FlyBaseID:	FBgn0052121	Length:	648	Species:	Drosophila melanogaster

Alignment Length:	468	Identity:	121/468 - (25%)
Similarity:	187/468 - (39%)	Gaps:	125/468 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    96 SSSSQQFCLRWNNYQTNLTTIFDQLLQNECFVDVTLACDGRSMKAHKMVLSACSPYFQTLL-AET 159
            :.|.|||||||:|:||:|.:....||......|||::.:||.::||::||||||.:|..:. |..
  Fly    24 NDSQQQFCLRWHNHQTSLLSTLPILLDQSHLTDVTISAEGRQLRAHRVVLSACSSFFMDIFRALE 88

  Fly   160 PCQHPIVIMRDVNWSDLKAIVEFMYRGEINVSQDQIGPLLRIAEMLKVRGLADVTHMEAATAAAA 224
            ...||::|:...::..:.:::.|||.||:||.::||..||.:||.|.::|||||.:......|.:
  Fly    89 ASNHPVIIIPGASFGAIVSLLTFMYSGEVNVYEEQIPMLLNLAETLGIKGLADVQNNNLPKTARS 153

  Fly   225 AASS------------ERMPSSPKESTSTSRTEHDREREAEELLAFMQPEKKLRT-------SDW 270
            ...|            || |::|..:.:.:.|.......:..|.....|...|.|       ...
  Fly   154 GGGSYMDTTNEKSSEFER-PTTPSPTPTPTLTPSHTPTPSHSLPLPQLPSAALNTPLLANKLGSV 217

  Fly   271 DPAELRLSPLERQQGRNVRKRRWPSADTIFNPPAPPSPL----------SSLIAAERMELE---- 321
            :.:.:..:|||     |:.|      ...|.|...|.||          :.|:|..:.:.:
  Fly   218 NSSGMGTTPLE-----NLFK------SLQFYPSLLPQPLNFSQTALNKTTELLAKYQQQCQLYQS 271

  Fly   322 -QKERERQRDC------SLMTPPP----------KPPMSSGSTVGATRRLETAIHALDMPSP--A 367
             .:|.:.:.||      ...:||.          |.|.||.:|..::.:   :......|:|  |
  Fly   272 GMQEDQLETDCFGSKRLKGDSPPKELRRLEKSLLKNPKSSSTTNSSSSK---SPQECSNPNPIVA 333

  Fly   368 ATPGPLSRSSRPHSQSPQ----------QQQAQQQGQLPLPLPLHPHHHASPAPHPSQTAGSAHH 422
            .:|..|:..:..|. |||          ...|..||||....|  |.:.|:..|..:|.|...||
  Fly   334 TSPVTLAPPTMAHF-SPQLPVVKCSSASYPSALGQGQLYSSKP--PLYSAAVTPTAAQQAAQMHH 395

  Fly   423 PASPAGDSRFPLGPA---------------------AAMAAARELSGLG-PGPSAEPRL------ 459
            ...|        ||:                     ||.|||....|:. ....:||.|
  Fly   396 HPQP--------GPSPYISAEDHAKLQLHIEQYQREAAAAAAAAAGGMALVSAKSEPNLLSLSAD 452

  Fly   460 --------PPPPP 464
                    |..||
  Fly   453 RDKSLATAPIKPP 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bab1	NP_728565.1	BTB	117..216	CDD:279045	39/99 (39%)
		BTB	128..213	CDD:197585	35/85 (41%)
		HTH_psq	569..614	CDD:283007
CG32121	NP_001097599.1	BTB	48..142	CDD:279045	37/93 (40%)
		BTB	56..149	CDD:197585	37/92 (40%)
		C2H2 Zn finger	474..494	CDD:275370
		C2H2 Zn finger	501..518	CDD:275370
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447069
Domainoid	1	1.000	69	1.000	Domainoid score	I9606
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000141
OrthoInspector	1	1.000	-	-		otm40394
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23110
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.940