DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bab1 and Btbd18

DIOPT Version :9

Sequence 1:	NP_728565.1	Gene:	bab1 / 38116	FlyBaseID:	FBgn0004870	Length:	977	Species:	Drosophila melanogaster
Sequence 2:	XP_002729248.1	Gene:	Btbd18 / 100363270	RGDID:	2323370	Length:	724	Species:	Rattus norvegicus

Alignment Length:	468	Identity:	96/468 - (20%)
Similarity:	168/468 - (35%)	Gaps:	115/468 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   122 QNECFVDVTLACDGRSMKAHKMVLSACSPYF-QTLLAETPCQHPIVIMR--DVNWSDLKAIVEFM 183
            |:..|.|..|..:|.::.||..:||||||:| :.|..|.|.|...|::.  .:....|:.:|:|:
  Rat    29 QSGVFCDALLQAEGEAVPAHCCILSACSPFFTERLERERPVQGRKVVLELGGLKIQTLRKLVDFL 93

  Fly   184 YRGEINVSQDQIGPLLRIAEMLKVRGLADVTHMEAATAAAAAAS---SERMPSSPKESTSTSRTE 245
            |..|:.|||::...:|..|..|:|..| :...:|......|...   :......|..:..::|..
  Rat    94 YTSEMEVSQEEAQDVLSAARQLRVSEL-ETLQLEGGKLVKAPQGRRLNRECLQPPSAAPISARVV 157

  Fly   246 HDREREAEELLAFMQPEKKLRTSDWDPAELRLSPLERQQGRNVRKRRWPSADTIFNPPAPPSPLS 310
            ..|.|....|.....|...        ..::|..|..::|.: :|...|:||.:
  Rat   158 VPRSRPRTPLPVTQTPSPL--------GAVKLKSLGEEEGAH-KKSNLPNADNL----------- 202

  Fly   311 SLIAAERMELEQKER---ERQRDCSLMTPPPKPPMSSGSTVGATRRLETAIHALDMPSPAATPGP 372
                ::.:.|::|.|   .::|..|                               || :...||
  Rat   203 ----SDTLLLKKKARVCLTQERSSS-------------------------------PS-SQREGP 231

  Fly   373 LSRSSRPHSQS-PQQQQAQQQGQLPLPLPLHPHHHASPAPH-----PSQTAGSAHHPASPAGDSR 431
            ....|.|.|.: |....:..:..||..:.|   ..:.|:||     ||...         :|.|.
  Rat   232 KENKSNPGSTALPSLYPSVDEQLLPRKIRL---SRSKPSPHVYTSKPSSML---------SGPSS 284

  Fly   432 FPLGPAAAMAAARELS----GLG---PGPSAEPRLPPPPPHHHGGGG---------------VGG 474
            .|..|...:...|.:|    |:.   ||..:..:..|.||.....||               |..
  Rat   285 MPTAPGRRLWRQRTVSEATQGVDKQKPGEVSTLQSTPDPPDVGKTGGKKQPSPESRAPASNSVEE 349

  Fly   475 GGVGGGGAGGVGSGGGSSLADDLEIKPGIAEMIREEERAKMMENSHAWMGATGSTLAADSYQYQL 539
            |.||......:.:|....:..:..|:       ..::..:::|:|.|  .....||.:...:.::
  Rat   350 GQVGRVKLRKIVNGTCWEVVQEPPIR-------NTQDSPQILESSDA--DEPPGTLLSSVNEQEI 405

  Fly   540 QSMWQKCWNTNQN 552
            .:..|.|.::.:|
  Rat   406 PARIQLCHDSPEN 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bab1	NP_728565.1	BTB	117..216	CDD:279045	32/96 (33%)
		BTB	128..213	CDD:197585	30/87 (34%)
		HTH_psq	569..614	CDD:283007
Btbd18	XP_002729248.1	BTB	24..123	CDD:279045	32/94 (34%)
Btbd18	XP_002729248.1	BTB	35..123	CDD:197585	30/88 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	59	1.000	Domainoid score	I10373
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000141
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910