Protein Alignment Glut1 and HXT5

DIOPT Version :10

• Sequence 1: NP_612073.2
• Gene: Glut1 / 38109
• FlyBaseID: FBgn0264574
• Length: 1440
• Species: Drosophila melanogaster
• Sequence 2: NP_011964.1
• Gene: HXT5 / 856496
• SGDID: S000001138
• Length: 592
• Species: Saccharomyces cerevisiae
• Alignment Length: 502
• Identity: 141/502 - (28%)
• Similarity: 233/502 - (46%)
• Gaps: 74/502 - (14%)

  Fly    12 FLTYSIFSAVLGMLQFGYNTGVIN-------------APEKNIENFMKDVYKDRYGEDISEEFIQ 63
            |::........|...||::||.|:             :...|...::.||   |.|
Yeast    85 FVSVCCLMVAFGGFVFGWDTGTISGFVRQTDFIRRFGSTRANGTTYLSDV---RTG--------- 137

  Fly    64 QLYSVAVSIFAIGGMLGGFSGGWMANRFGRKGGLLLNNVLGIAGACLMGFTKVSHSYEMLFLGRF 128
                :.||||.||..:||.....:.:.:|||.||:...|:...| .::....:...|: .|:||.
Yeast   138 ----LMVSIFNIGCAIGGIVLSKLGDMYGRKIGLMTVVVIYSIG-IIIQIASIDKWYQ-YFIGRI 196

  Fly   129 IIGVNCGLNTSLVPMYISEIAPLNLRGGLGTVNQLAVTVGLLLSQVLGIEQILGTNEG------- 186
            |.|:..|..|.|.||.|||::|..|||.|.:..||.:|.|:.|...        ||.|
Yeast   197 ISGLGVGGITVLAPMLISEVSPKQLRGTLVSCYQLMITFGIFLGYC--------TNFGTKNYSNS 253

  Fly   187 --WPILLGLAICPAILQLILLPVCPESPRYLLITKQWEEEARKALRRLRASGSVEE------DIE 243
              |.:.|||....:|..::.:...|||||||:...: .|||:::|  .||:.:.|:      ::|
Yeast   254 VQWRVPLGLCFAWSIFMIVGMTFVPESPRYLVEVGK-IEEAKRSL--ARANKTTEDSPLVTLEME 315

  Fly   244 EMRAEERAQQSESHISTMELIC-SPTLRPPLIIGIVMQLSQQFSGINAVFYYSTSLFMSSGLTEE 307
            ..::...|::.....|..||:. .|.:....::|:::|..||.:|.|..|||.|::|.:.|| |:
Yeast   316 NYQSSIEAERLAGSASWGELVTGKPQMFRRTLMGMMIQSLQQLTGDNYFFYYGTTIFQAVGL-ED 379

  Fly   308 SAKFATIGIGAIMVVMTLVSIPLMDRTGRRTLHLYGLGGM---FIFSIFITISFLIKEMIDWMS- 368
            |.:.|.: :|.:..|.|..|:..:||.|||...|:|..||   ::....:.::.|.....|..|
Yeast   380 SFETAIV-LGVVNFVSTFFSLYTVDRFGRRNCLLWGCVGMICCYVVYASVGVTRLWPNGQDQPSS 443

  Fly   369 ----YLSVVATLGFVVFFAVGPGSIPWMITAELFSQGPRPSAMAIAVLVNWMANFVVGIGFPSMK 429
                ...:|....::..||.....:.:::.:|.:....|..||:||...||:..|::....|.:.
Yeast   444 KGAGNCMIVFACFYIFCFATTWAPVAYVLISESYPLRVRGKAMSIASACNWIWGFLISFFTPFIT 508

  Fly   430 TALE---NYTFLPFSVFLAIFWIFTYKKVPETKNKTFEEILALFRHN 473
            :|:.   .|.|:...|| |.|::|.:  |||||..|.||:..::..|
Yeast   509 SAINFYYGYVFMGCMVF-AYFYVFFF--VPETKGLTLEEVNEMYEEN 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glut1	NP_612073.2	MFS_GLUT_Class1	15..461	CDD:340989	136/485 (28%)
HXT5	NP_011964.1	Sugar_tr	89..549	CDD:395036	139/493 (28%)