Protein Alignment Glut1 and HXT1

DIOPT Version :10

• Sequence 1: NP_612073.2
• Gene: Glut1 / 38109
• FlyBaseID: FBgn0264574
• Length: 1440
• Species: Drosophila melanogaster
• Sequence 2: NP_011962.1
• Gene: HXT1 / 856494
• SGDID: S000001136
• Length: 570
• Species: Saccharomyces cerevisiae
• Alignment Length: 497
• Identity: 139/497 - (27%)
• Similarity: 226/497 - (45%)
• Gaps: 68/497 - (13%)

  Fly     8 GLTFFLTYSIFSAVL--GMLQFGYNTGVINAPEKNIENFMKDV-YKDRYG---EDISEEFIQQLY 66
            |...::|.||...::  |...||::||.|:       .|:... :..|:|   .|.|....:...
Yeast    58 GKGVYVTVSICCVMVAFGGFIFGWDTGTIS-------GFVAQTDFLRRFGMKHHDGSHYLSKVRT 115

  Fly    67 SVAVSIFAIGGMLGGFSGGWMANRFGRKGGLLLNNVLGIAGACLMGFTKVSHSYEMLFLGRFIIG 131
            .:.||||.||..:||.....:.:.:||:.||::..|:...| .::....::..|: .|:||.|.|
Yeast   116 GLIVSIFNIGCAIGGIVLAKLGDMYGRRIGLIVVVVIYTIG-IIIQIASINKWYQ-YFIGRIISG 178

  Fly   132 VNCGLNTSLVPMYISEIAPLNLRGGLGTVNQLAVTVGLLLSQVLGIEQILGTNEG---------W 187
            :..|..|.|.||.|||:||..:||.|.:..|:.:|:|:.|...        ||.|         |
Yeast   179 LGVGGITVLSPMLISEVAPSEMRGTLVSCYQVMITLGIFLGYC--------TNFGTKNYSNSVQW 235

  Fly   188 PILLGLAICPAILQLILLPVCPESPRYLLITKQWEEEARKALRRLRAS-----------GSVEED 241
            .:.|||....|:..:..:...|||||||:...: .:|||.:|.::...           .::|..
Yeast   236 RVPLGLCFAWALFMIGGMMFVPESPRYLVEAGR-IDEARASLAKVNKCPPDHPYIQYELETIEAS 299

  Fly   242 IEEMRAEERAQQSESHISTMELICSPTLRPPLIIGIVMQLSQQFSGINAVFYYSTSLFMSSGLTE 306
            :|||||...|...|....      .|.:....::||::|..||.:|.|..|||.|.:|.:.||::
Yeast   300 VEEMRAAGTASWGELFTG------KPAMFQRTMMGIMIQSLQQLTGDNYFFYYGTIVFQAVGLSD 358

  Fly   307 ESAKFAT-IGIGAIMVVMTLVSIPLMDRTGRRTLHLYGLGGM---FIFSIFITISFLIKEMIDWM 367
               .|.| |..|.:....|..|:..:||.|||...::|..||   ::....:.::.|.....|..
Yeast   359 ---SFETSIVFGVVNFFSTCCSLYTVDRFGRRNCLMWGAVGMVCCYVVYASVGVTRLWPNGQDQP 420

  Fly   368 S-----YLSVVATLGFVVFFAVGPGSIPWMITAELFSQGPRPSAMAIAVLVNWMANFVVGIGFPS 427
            |     ...:|....::..||.....|.:::.:|.|....:...|:||...||:..|::....|.
Yeast   421 SSKGAGNCMIVFACFYIFCFATTWAPIAYVVISECFPLRVKSKCMSIASAANWIWGFLISFFTPF 485

  Fly   428 MKTALE---NYTFLPFSVFLAIFWIFTYKKVPETKNKTFEEI 466
            :..|:.   .|.|:...|| |.|::|.:  |||||..:.||:
Yeast   486 ITGAINFYYGYVFMGCMVF-AYFYVFFF--VPETKGLSLEEV 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glut1	NP_612073.2	MFS_GLUT_Class1	15..461	CDD:340989	135/483 (28%)
HXT1	NP_011962.1	Sugar_tr	68..528	CDD:395036	135/487 (28%)