Protein Alignment Glut1 and HXT4

DIOPT Version :10

• Sequence 1: NP_612073.2
• Gene: Glut1 / 38109
• FlyBaseID: FBgn0264574
• Length: 1440
• Species: Drosophila melanogaster
• Sequence 2: NP_011960.2
• Gene: HXT4 / 856492
• SGDID: S000001134
• Length: 576
• Species: Saccharomyces cerevisiae
• Alignment Length: 497
• Identity: 144/497 - (28%)
• Similarity: 235/497 - (47%)
• Gaps: 68/497 - (13%)

  Fly    12 FLTYSI--FSAVLGMLQFGYNTGVIN---APEKNIENFMKDVYKDRYGEDISEEFIQQLYS-VAV 70
            ::|.||  .....|...||::||.|:   |....|..|....:...|       ::.::.: :.|
Yeast    68 YVTVSICCLMVAFGGFVFGWDTGTISGFVAQTDFIRRFGMKHHDGTY-------YLSKVRTGLIV 125

  Fly    71 SIFAIGGMLGGFSGGWMANRFGRKGGLLLNNVLGIAGACLMGFTKVSHSYEMLFLGRFIIGVNCG 135
            |||.||..:||.....:.:.:|||.||::..|:.|.| .::....::..|: .|:||.|.|:..|
Yeast   126 SIFNIGCAIGGIILAKLGDMYGRKMGLIVVVVIYIIG-IIIQIASINKWYQ-YFIGRIISGLGVG 188

  Fly   136 LNTSLVPMYISEIAPLNLRGGLGTVNQLAVTVGLLLSQVLGIEQILGTNEG---------WPILL 191
            ....|.||.|||::|.::||.|.:..||.:|:|:.|...        ||.|         |.:.|
Yeast   189 GIAVLSPMLISEVSPKHIRGTLVSCYQLMITLGIFLGYC--------TNYGTKTYTNSVQWRVPL 245

  Fly   192 GLAICPAILQLILLPVCPESPRYLLITKQWEEEARKALRRLRASGSVEED-------IEEMRAEE 249
            ||....|:..:..:...|||||||:...:.||    |.|.:..|..|..|       :|.::|..
Yeast   246 GLGFAWALFMIGGMTFVPESPRYLVEVGKIEE----AKRSIALSNKVSADDPAVMAEVEVVQATV 306

  Fly   250 RAQQSESHISTMELICSPT-LRPPLIIGIVMQLSQQFSGINAVFYYSTSLFMSSGLTEESAKFAT 313
            .|::...:.|..|:..:.| :...||:|.::|..||.:|.|..|||.|::|.:.|| |:|.: .:
Yeast   307 EAEKLAGNASWGEIFSTKTKVFQRLIMGAMIQSLQQLTGDNYFFYYGTTVFTAVGL-EDSFE-TS 369

  Fly   314 IGIGAIMVVMTLVSIPLMDRTGRRTLHLYGLGGM-FIFSIFITISFLIKEMIDW----------- 366
            |.:|.:....|.|.|.|::|.|||...|:|...| ....:|.::.  :..:  |
Yeast   370 IVLGIVNFASTFVGIFLVERYGRRRCLLWGAASMTACMVVFASVG--VTRL--WPNGKKNGSSKG 430

  Fly   367 MSYLSVVATLGFVVFFAVGPGSIPWMITAELFSQGPRPSAMAIAVLVNWMANFVVGIGFPSMKTA 431
            .....:|.|..::..||.....||:::.:|.|....:...||||...||:..|::|...|.:..|
Yeast   431 AGNCMIVFTCFYLFCFATTWAPIPFVVNSETFPLRVKSKCMAIAQACNWIWGFLIGFFTPFISGA 495

  Fly   432 LE---NYTFLPFSVFLAIFWIFTYKKVPETKNKTFEEILALF 470
            ::   .|.|:...|| :.|::|.:  |||||..|.||:..|:
Yeast   496 IDFYYGYVFMGCLVF-SYFYVFFF--VPETKGLTLEEVNTLW 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glut1	NP_612073.2	MFS_GLUT_Class1	15..461	CDD:340989	139/483 (29%)
HXT4	NP_011960.2	Sugar_tr	74..534	CDD:395036	140/489 (29%)