Protein Alignment Glut1 and ITR2

DIOPT Version :9

• Sequence 1: NP_612073.2
• Gene: Glut1 / 38109
• FlyBaseID: FBgn0264574
• Length: 1440
• Species: Drosophila melanogaster
• Sequence 2: NP_014538.2
• Gene: ITR2 / 854050
• SGDID: S000005463
• Length: 609
• Species: Saccharomyces cerevisiae
• Alignment Length: 532
• Identity: 149/532 - (28%)
• Similarity: 247/532 - (46%)
• Gaps: 70/532 - (13%)

  Fly    11 FFLTYSIFSAVLGMLQFGYNTGVINAP----EKNIENFMKDVYKDRYGEDISEEFIQQLYSVAVS 71
            |.:|.:..:::.|.: |||:||.|::.    .::::|.:.     .|||       ::|.:.|.|
Yeast   108 FIITLTFVASISGFM-FGYDTGYISSALISINRDLDNKVL-----TYGE-------KELITAATS 159

  Fly    72 IFAIGGMLGGFSGGWMANRFGRKGGLLLNNVLGIAGACLMGFTKVSHSYEMLFLGRFIIGVNCGL 136
               :|.::.....|..|:.|||:..|:.:|::.:.||.|.   ..:|.:..:..||.|:|...|:
Yeast   160 ---LGALITSVGAGTAADVFGRRPCLMFSNLMFLIGAILQ---ITAHKFWQMAAGRLIMGFGVGI 218

  Fly   137 NTSLVPMYISEIAPLNLRGGLGTVNQLAVTVGLLLSQVLGIEQILGTN---EGWPILLGLAICPA 198
            .:.:.|::||||||..:||.|..:|.|.:|.|.|::...|    .|.|   .||.||:||::.|.
Yeast   219 GSLISPLFISEIAPKMIRGRLTVINSLWLTGGQLIAYGCG----AGLNHVKNGWRILVGLSLIPT 279

  Fly   199 ILQLILLPVCPESPRYLLITKQWEEEARKALRRLRASGSVEEDIEEMRAEERAQQSES------- 256
            :||.......|::||| .:.|...:.|:..|:  |:..:.|::|.:.:.||.:..::|
Yeast   280 VLQFSFFCFLPDTPRY-YVMKGDLKRAKMVLK--RSYVNTEDEIIDQKVEELSSLNQSIPGKNPI 341

  Fly   257 ---HISTMELICSPTLRPPLIIGIVMQLSQQFSGINAVFYYSTSLFMSSGLTEESAKFATIGIGA 318
               .....||...|:....||||..:|..|||:|.|::.|:|.::|.:.|....||  .:|.:..
Yeast   342 TKFWNMVKELHTVPSNFRALIIGCGLQAIQQFTGWNSLMYFSGTIFETVGFKNSSA--VSIIVSG 404

  Fly   319 IMVVMTLVSIPLMDRTGRRTLHLYGLGGMFIFSIFITISFLIKEMIDWMSYLSVVATLGF----- 378
            ...|.||::...:|:.|||.:.|.||.||.:..:...|:|.... |.:....:|||:.||
Yeast   405 TNFVFTLIAFFCIDKIGRRYILLIGLPGMTVALVICAIAFHFLG-IKFNGADAVVASDGFSSWGI 468

  Fly   379 ---------VVFFAVGPGSIPWMITAELFSQGPRPSAMAIAVLVNWMANFVVGIGFPSMKTALEN 434
                     ..|:|:|.|::||. .:|||.|..|....:.|...||..:.|:...|.:|   |:|
Yeast   469 VIIVFIIVYAAFYALGIGTVPWQ-QSELFPQNVRGVGTSYATATNWAGSLVIASTFLTM---LQN 529

  Fly   435 Y----TFLPFSVFLAIFWIFTYKKVPETKNKTFEEILALFRHNNGRSMLNCTNSLEPQSMNSGIE 495
            .    ||..|:....:..||.|...||......||:..:.:................|.:..|..
Yeast   530 ITPTGTFSFFAGVACLSTIFCYFCYPELSGLELEEVQTILKDGFNIKASKALAKKRKQQVAEGAA 594

  Fly   496 HAALMVSEEKTQ 507
            |..|..  |.||
Yeast   595 HHKLKF--EPTQ 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glut1	NP_612073.2	MFS	17..452	CDD:119392	135/469 (29%)
		Sugar_tr	18..470	CDD:278511	140/486 (29%)
ITR2	NP_014538.2	MFS_HMIT_like	115..556	CDD:340918	136/473 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910