Protein Alignment Glut1 and HXT8

DIOPT Version :10

• Sequence 1: NP_612073.2
• Gene: Glut1 / 38109
• FlyBaseID: FBgn0264574
• Length: 1440
• Species: Drosophila melanogaster
• Sequence 2: NP_012321.1
• Gene: HXT8 / 853216
• SGDID: S000003750
• Length: 569
• Species: Saccharomyces cerevisiae
• Alignment Length: 527
• Identity: 137/527 - (25%)
• Similarity: 226/527 - (42%)
• Gaps: 58/527 - (11%)

  Fly    12 FLTYSIFSAVL--GMLQFGYNTGVINAPEKNIENFMKDVYKDRYGEDISEEFIQQLYSV----AV 70
            :.|.||....:  |....|::||.|:. ..|..:|::     |:|.....:....|.:|    .|
Yeast    63 YATVSIMCLCMAFGGFMSGWDTGTISG-FVNQTDFLR-----RFGNYSHSKNTYYLSNVRTGLIV 121

  Fly    71 SIFAIGGMLGGFSGGWMANRFGRKGGLLLNNVLGIAGACLMGFTKVSHSYEMLFLGRFIIGVNCG 135
            |||.:|..:|......:.:.:||..||::..|:.:.|..:. ...:...|: .|:||.|.|:..|
Yeast   122 SIFNVGSAIGCLFLSKLGDIYGRCMGLIIVIVVYMVGIVIQ-IASIDKWYQ-YFIGRIIAGIGAG 184

  Fly   136 LNTSLVPMYISEIAPLNLRGGLGTVNQLAVTVGLLLSQVLGIEQILGTNEG---------WPILL 191
            ..:.|.||.|||.||.::||.|....||.||..:.|...        ||.|         |.:.|
Yeast   185 SISVLAPMLISETAPKHIRGTLLACWQLMVTFAIFLGYC--------TNYGTKTYSNSVQWRVPL 241

  Fly   192 GLAICPAILQLILLPVCPESPRYLLITKQWEEEARKALRRLRAS---GSVEEDIEEMRAEERAQQ 253
            ||....||:.:..:...|||||:|:...:.|:......:..:.|   .:|..:|:.:.|...|::
Yeast   242 GLCFAWAIIMIGGMTFVPESPRFLVQVGKIEQAKASFAKSNKLSVDDPAVVAEIDLLVAGVEAEE 306

  Fly   254 SESHISTMELICSPT-LRPPLIIGIVMQLSQQFSGINAVFYYSTSLFMSSGLTEESAKFAT-IGI 316
            :....|..||....| :...|.:.:::...||.:|.|..|||.|::|.|.|:.:   .|.| |.:
Yeast   307 AMGTASWKELFSRKTKVFQRLTMTVMINSLQQLTGDNYFFYYGTTIFKSVGMND---SFETSIVL 368

  Fly   317 GAIMVVMTLVSIPLMDRTGRRTLHLYGLGGMFIFSIFITISFLIKEMIDWMSYLS--------VV 373
            |.:.......|:..:|:.|||...|.|...|....:......:.:...:..|..|        :|
Yeast   369 GIVNFASCFFSLYSVDKLGRRRCLLLGAATMTACMVIYASVGVTRLYPNGKSEPSSKGAGNCTIV 433

  Fly   374 ATLGFVVFFAVGPGSIPWMITAELFSQGPRPSAMAIAVLVNWMANFVVGIGFPSMKTALENYTFL 438
            .|..::..|:...|.:.::|.:|.|....|...|::|...|.:..|::|...|.:.:|:..|...
Yeast   434 FTCFYIFCFSCTWGPVCYVIISETFPLRVRSKCMSVATAANLLWGFLIGFFTPFITSAINFYYGY 498

  Fly   439 PFSVFLAIFWIFTYKKVPETKNKTFEEILALFRHNNGRSMLNC-TNSLEPQSMNSGIEHAALMVS 502
            .|...||..:.:.:..|||||..|.||:..::..    .:|.. :.|..|.|...|      ...
Yeast   499 VFMGCLAFSYFYVFFFVPETKGLTLEEVDEMWMD----GVLPWKSESWVPASRRDG------DYD 553

  Fly   503 EEKTQHD 509
            .||.|||
Yeast   554 NEKLQHD 560

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glut1	NP_612073.2	MFS_GLUT_Class1	15..461	CDD:340989	123/473 (26%)
HXT8	NP_012321.1	Sugar_tr	69..530	CDD:395036	124/479 (26%)