Protein Alignment Glut1 and RGT2

DIOPT Version :10

• Sequence 1: NP_612073.2
• Gene: Glut1 / 38109
• FlyBaseID: FBgn0264574
• Length: 1440
• Species: Drosophila melanogaster
• Sequence 2: NP_010143.1
• Gene: RGT2 / 851417
• SGDID: S000002297
• Length: 763
• Species: Saccharomyces cerevisiae
• Alignment Length: 520
• Identity: 139/520 - (26%)
• Similarity: 236/520 - (45%)
• Gaps: 80/520 - (15%)

  Fly    17 IFSAVLGMLQFGYNTGVINAPEKNIENFMKDV-YKDRYGEDISEEFIQQLYSVAVSIFAIGGMLG 80
            ||.||.|.| |||:||:||:        :.|: |...|.......|.....::.||..::|...|
Yeast   104 IFVAVGGFL-FGYDTGLINS--------ITDMPYVKTYIAPNHSYFTTSQIAILVSFLSLGTFFG 159

  Fly    81 GFSGGWMANRFGRKGGLL--------LNNVLGIAGACLMGFTKVSHSYEMLFLGRFIIGVNCGLN 137
            .....::::.:|||..::        :.|.|.:|...|:          :|.:||.|.|:..|:.
Yeast   160 ALIAPYISDSYGRKPTIMFSTAVIFSIGNSLQVASGGLV----------LLIVGRVISGIGIGII 214

  Fly   138 TSLVPMYISEIAPLNLRGGLGTVNQLAVTVGLLLSQVLGIEQILGTN-----EGWPILLGLAICP 197
            :::||:|.:|.|..||||.:.:..|.|:|:|||:|..:.    .||:     ..:.|.:||....
Yeast   215 SAVVPLYQAEAAQKNLRGAIISSYQWAITIGLLVSSAVS----QGTHSKNGPSSYRIPIGLQYVW 275

  Fly   198 AILQLILLPVCPESPRYLLITKQWEEEARKALRRLRA----SGSVEEDIEEMRAEERAQQSESHI 258
            :.:..:.:...||||||.:: |....:|.|:|..||.    ...:.|::.|::|....:.|....
Yeast   276 SSILAVGMIFLPESPRYYVL-KDELNKAAKSLSFLRGLPIEDPRLLEELVEIKATYDYEASFGPS 339

  Fly   259 STMELICSPTLRPPLII----GIVMQLSQQFSGINAVFYYSTSLFMSSGLTEESAKFATIGIGAI 319
            :.::...:...||..|:    ||.:|..||.||||.:|||..:.|.::|:  :::...:....|:
Yeast   340 TLLDCFKTSENRPKQILRIFTGIAIQAFQQASGINFIFYYGVNFFNNTGV--DNSYLVSFISYAV 402

  Fly   320 MVVMTLVSIPLMDRTGRRTLHLYGLGGMFIFSIFITISFLIKEMIDWMSYLSVVATLGFVVF--- 381
            .|..::..:.|:||.|||.:.|.|       .:.:.|:.|:..::......:|||:...:.|
Yeast   403 NVAFSIPGMYLVDRIGRRPVLLAG-------GVIMAIANLVIAIVGVSEGKTVVASKIMIAFICL 460

  Fly   382 ----FAVGPGSIPWMITAELFSQGPRPSAMAIAVLVNWMANF--------VVGIGFPSMKTALEN 434
                |:...|.:.|:::|||:..|.|....||....||:.||        :|.:|  |..:::..
Yeast   461 FIAAFSATWGGVVWVVSAELYPLGVRSKCTAICAAANWLVNFTCALITPYIVDVG--SHTSSMGP 523

  Fly   435 YTFLPFSVFLAIFWIFTYKKVPETKNKTFEEILALFRHNNGRSMLNCTNSLEPQSMNSGIEHAAL 499
            ..|..:.....:..|..|..|.||:..|.|||..|||        ...||:.....|..|....|
Yeast   524 KIFFIWGGLNVVAVIVVYFAVYETRGLTLEEIDELFR--------KAPNSVISSKWNKKIRKRCL 580

  Fly   500  499
            Yeast   581  580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glut1	NP_612073.2	MFS_GLUT_Class1	15..461	CDD:340989	127/480 (26%)
RGT2	NP_010143.1	SP	76..555	CDD:273317	129/485 (27%)