Protein Alignment Glut1 and SNF3

DIOPT Version :10

• Sequence 1: NP_612073.2
• Gene: Glut1 / 38109
• FlyBaseID: FBgn0264574
• Length: 1440
• Species: Drosophila melanogaster
• Sequence 2: NP_010087.1
• Gene: SNF3 / 851333
• SGDID: S000002353
• Length: 884
• Species: Saccharomyces cerevisiae
• Alignment Length: 734
• Identity: 182/734 - (24%)
• Similarity: 301/734 - (41%)
• Gaps: 177/734 - (24%)

  Fly    17 IFSAVLGMLQFGYNTGVINAPEKNIENFMKDVYKDRYGEDISEEFIQQLYSVAVSIFAIGGMLGG 81
            :|.||.|.| |||:||:||:...  .|::|......:     :.|..|..|:.||..::|...|.
Yeast   102 VFVAVGGFL-FGYDTGLINSITS--MNYVKSHVAPNH-----DSFTAQQMSILVSFLSLGTFFGA 158

  Fly    82 FSGGWMANRFGRKGGLLLNN--VLGIAGACLMGFTKVSHSYEMLFLGRFIIGVNCGLNTSLVPMY 144
            .:..::::.:|||..::.:.  :..|..:..:|...::    :|.:||.|.|:..|..:::||:|
Yeast   159 LTAPFISDSYGRKPTIIFSTIFIFSIGNSLQVGAGGIT----LLIVGRVISGIGIGAISAVVPLY 219

  Fly   145 ISEIAPLNLRGGLGTVNQLAVTVGLLLSQVLGIEQILGTN-----EGWPILLGLAICPAILQLIL 204
            .:|....:|||.:.:..|.|:|.|||:|..:.    .||:     ..:.|.:||....:....|.
Yeast   220 QAEATHKSLRGAIISTYQWAITWGLLVSSAVS----QGTHARNDASSYRIPIGLQYVWSSFLAIG 280

  Fly   205 LPVCPESPRYLLITKQWEEEARKALRRLRA-----SGSVEEDIEEMRAEERAQQSESHISTMELI 264
            :...||||||.:: |...:||.|:|..||.     ||.:|| :.|::|....:.|....:.::..
Yeast   281 MFFLPESPRYYVL-KDKLDEAAKSLSFLRGVPVHDSGLLEE-LVEIKATYDYEASFGSSNFIDCF 343

  Fly   265 CSPTLRPP----LIIGIVMQLSQQFSGINAVFYYSTSLFMSSGLTEE-SAKFATIGIGAIMVVMT 324
            .|...||.    :..||.:|..|||||||.:|||..:.|..:|::.. ...|.|.   |:.||..
Yeast   344 ISSKSRPKQTLRMFTGIALQAFQQFSGINFIFYYGVNFFNKTGVSNSYLVSFITY---AVNVVFN 405

  Fly   325 LVSIPLMDRTGRRTLHLYGLGGMFIFSIFITISFLIKEMIDWMSYLSVVATLGFVVF-------F 382
            :..:..::..|||.:.:.|       .:.:||:..|..::. .|..:|.|....:.|       |
Yeast   406 VPGLFFVEFFGRRKVLVVG-------GVIMTIANFIVAIVG-CSLKTVAAAKVMIAFICLFIAAF 462

  Fly   383 AVGPGSIPWMITAELFSQGPRPSAMAIAVLVNWMANFVVGIGFPSMKTALENYTFLPFSVFLAIF 447
            :...|.:.|:|:|||:..|.|....||....||:.||:..:..|.:.....:.:.|...:|  ..
Yeast   463 SATWGGVVWVISAELYPLGVRSKCTAICAAANWLVNFICALITPYIVDTGSHTSSLGAKIF--FI 525

  Fly   448 W--------IFTYKKVPETKNKTFEEILALFRHNNGRSMLNCTNSLEPQSMNSGIEHAALMVSEE 504
            |        |..|..|.|||..|.|||..|:       :.:.|..:.|: .|..|...||
Yeast   526 WGSLNAMGVIVVYLTVYETKGLTLEEIDELY-------IKSSTGVVSPK-FNKDIRERAL----- 577

  Fly   505 KTQHDSL--------------------FGTTSFSLTVEG----------MGPYP----LSDSTNL 535
            |.|:|.|                    .....|..|:.|          :...|    :..||.:
Yeast   578 KFQYDPLQRLEDGKNTFVAKRNNFDDETPRNDFRNTISGEIDHSPNQKEVHSIPERVDIPTSTEI 642

  Fly   536 L-GPGSSSYGPGGVLGLAGS----------------------GSGLGGQCYTNYGTNLQTPQAAR 577
            | .|..||   |..:.::.|                      |:|||...|.....:|.:
Yeast   643 LESPNKSS---GMTVPVSPSLQDVPIPQTTEPAEIRTKYVDLGNGLGLNTYNRGPPSLSS----- 699

  Fly   578 KCHYDEVDDYSFRRHSAHGRITQMKGKPLILGPTIKKDKKKERT-----DWL--------TAS-- 627
                |..:||:               :..|.||:.:.|:....|     |::        |||
Yeast   700 ----DSSEDYT---------------EDEIGGPSSQGDQSNRSTMNDINDYMARLIHSTSTASNT 745

  Fly   628 -ERFLEGGRSTHQGRSAAS 645
             ::| .|.:||.:..:|:|
Yeast   746 TDKF-SGNQSTLRYHTASS 763

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glut1	NP_612073.2	MFS_GLUT_Class1	15..461	CDD:340989	131/475 (28%)
SNF3	NP_010087.1	MFS_HXT	99..556	CDD:340914	135/484 (28%)