DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Glut1 and SGB1

DIOPT Version :9

Sequence 1:	NP_612073.2	Gene:	Glut1 / 38109	FlyBaseID:	FBgn0264574	Length:	1440	Species:	Drosophila melanogaster
Sequence 2:	NP_178100.3	Gene:	SGB1 / 844321	AraportID:	AT1G79820	Length:	495	Species:	Arabidopsis thaliana

Alignment Length:	456	Identity:	138/456 - (30%)
Similarity:	224/456 - (49%)	Gaps:	33/456 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 IFSAVLGMLQFGYNTGVINAPEKNIENFMKDVYKDRYGEDISEEFIQQLYSVAVSIFAIGGMLGG 81
            :..|.|..|.|||:.||:|   :.:|:...|:  ...|..|:|       .:.||....|..:|.
plant    58 VLVASLTSLLFGYHLGVVN---ETLESISIDL--GFSGNTIAE-------GLVVSTCLGGAFIGS 110

  Fly    82 FSGGWMANRFGRKGGLLLNNVLGIAGACLMGFTKVSHSYEML---FLGRFIIGVNCGLNTSLVPM 143
            ...|.:|:..||:....|:.:..|.||      .||.|.|.|   .||||::|:..|:..|:..:
plant   111 LFSGLVADGVGRRRAFQLSALPMIVGA------SVSASTESLMGMLLGRFLVGIGMGIGPSVTAL 169

  Fly   144 YISEIAPLNLRGGLGTVNQLAVTVGLLLSQVLGI--EQILGTNEGWPILLGLAICPAILQLILLP 206
            |::|::|..:||..|:..|:|..:|||.|...||  :..||   .|.|...::..||.:..:.:.
plant   170 YVTEVSPAYVRGTYGSSTQIATCIGLLGSLFAGIPAKDNLG---WWRICFWISTVPAAMLAVFME 231

  Fly   207 VCPESPRYLLITKQWEEEARKALRRLRASGSVEEDIEEMRAEERAQQSESHISTMELICSPTLRP 271
            :|.|||:: |..:....||.....:|.....|:..:.|:...:|...::| ....||:...:.|
plant   232 LCVESPQW-LFKRGRAAEAEAVFEKLLGGSYVKAAMAELVKSDRGDDADS-AKLSELLFGRSFR- 293

  Fly   272 PLIIGIVMQLSQQFSGINAVFYYSTSLFMSSGLTEESAKFATIGIGAIMVVMTLVSIPLMDRTGR 336
            .:.||..:...||.||||||||:|:::|..:|:...|   |.|.:|...::.:.|::.|||:.||
plant   294 VVFIGSTLFALQQLSGINAVFYFSSTVFKKAGVPSAS---ANICVGVCNLLGSTVAVVLMDKLGR 355

  Fly   337 RTLHLYGLGGMFIFSIFITISFLIKEMIDWMSYLSVVATLGFVVFFAVGPGSIPWMITAELFSQG 401
            :.|.:....||.:......|::..........:|||...|.||:.||.|.|.:|.::.:|:....
plant   356 KVLLIGSFAGMAVSLGLQAIAYTSLPSPFGTLFLSVGGMLLFVLSFATGAGPVPSLLLSEICPGR 420

  Fly   402 PRPSAMAIAVLVNWMANFVVGIGFPSMKTALENYTF-LPFSVFLAIFWIFTYKKVPETKNKTFEE 465
            .|.:|:|:.:.|:|:.||.||:.|..|...|.:... ..|..|..:..||..|.|.|||.|:.:|
plant   421 LRATALAVCLAVHWVINFFVGLLFLRMLEQLGSVLLNAIFGFFCVVAVIFVQKNVVETKGKSLQE 485

  Fly   466 I 466
            |
plant   486 I 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Glut1	NP_612073.2	MFS	17..452	CDD:119392	130/440 (30%)
Glut1	NP_612073.2	Sugar_tr	18..470	CDD:278511	138/455 (30%)
SGB1	NP_178100.3	MFS_GLUT_like	60..477	CDD:340873	132/443 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D326501at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23503
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020