DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Glut1 and STP9

DIOPT Version :9

Sequence 1:	NP_612073.2	Gene:	Glut1 / 38109	FlyBaseID:	FBgn0264574	Length:	1440	Species:	Drosophila melanogaster
Sequence 2:	NP_175449.1	Gene:	STP9 / 841453	AraportID:	AT1G50310	Length:	517	Species:	Arabidopsis thaliana

Alignment Length:	480	Identity:	137/480 - (28%)
Similarity:	241/480 - (50%)	Gaps:	34/480 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 GLTFFLTYSIFSAVLGMLQFGYNTGV---INAPEKNIENFMKDVYKDRY---GEDISEEFIQQLY 66
            |:|.|:..:...|.:|.|.|||:.|:   :.:.|:.:..|..:|.|..:   .|....:|..||.
plant    20 GVTVFVIMTCIVAAMGGLLFGYDLGISGGVTSMEEFLSKFFPEVDKQMHEARRETAYCKFDNQLL 84

  Fly    67 SVAVSIFAIGGMLGGFSGGWMANRFGRKGGLLLNNVLGIAGACLMGF-TKVSHSYEMLFLGRFII 130
            .:..|...:..:...|....:..::|||..:.:..|..:.|:....| |.|:    ||.:||.::
plant    85 QLFTSSLYLAALASSFVASAVTRKYGRKISMFVGGVAFLIGSLFNAFATNVA----MLIVGRLLL 145

  Fly   131 GVNCGLNTSLVPMYISEIAPLNLRGGLGTVNQLAVTVGLLLSQVL--GIEQILGTNEGWPILLGL 193
            ||..|......|:|:||:||..:||.|....|:|:|:|:|::.::  |..|:  ...||.:.|||
plant   146 GVGVGFANQSTPVYLSEMAPAKIRGALNIGFQMAITIGILIANLINYGTSQM--AKNGWRVSLGL 208

  Fly   194 AICPAILQLILLPVCPESPRYLLITKQWEEEARKALRRLRASGSVEEDIEEM-RAEERAQQSESH 257
            |..||::.:|...|.|::|..:|...:: |:||:.|:::|.:.:|:|:.::: .|.|.|::.::
plant   209 AAVPAVIMVIGSFVLPDTPNSMLERGKY-EQAREMLQKIRGADNVDEEFQDLCDACEAAKKVDN- 271

  Fly   258 ISTMELICSPTLRPPLIIGIVMQLSQQFSGINAVFYYSTSLFMSSGLTEESAKFATIGIGAIMVV 322
             ....:......||.|:....:...||.:|||.:.:|:..||.:.|..::::..:.:..||:.||
plant   272 -PWKNIFQQAKYRPALVFCSAIPFFQQITGINVIMFYAPVLFKTLGFADDASLISAVITGAVNVV 335

  Fly   323 MTLVSIPLMDRTGRRTLHLYG----LGGMFIFSIFITISF-------LIKEMIDWMSYLSVVATL 376
            .|||||..:||.|||.|.|.|    :....:....|.:.|       |.....||:  |:.:..
plant   336 STLVSIYAVDRYGRRILFLEGGIQMIVSQIVVGTLIGMKFGTTGSGTLTPATADWI--LAFICL- 397

  Fly   377 GFVVFFAVGPGSIPWMITAELFSQGPRPSAMAIAVLVNWMANFVVGIGFPSMKTALENYTFLPFS 441
             :|..||...|.:.|::.:|:.....||:..||.|.||....|::|..|.:|...::...|..|.
plant   398 -YVAGFAWSWGPLGWLVPSEICPLEIRPAGQAINVSVNMFFTFLIGQFFLTMLCHMKFGLFYFFG 461

  Fly   442 VFLAIFWIFTYKKVPETKNKTFEEI 466
            ..:|:..:|.|..:||||....||:
plant   462 GMVAVMTVFIYFLLPETKGVPIEEM 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Glut1	NP_612073.2	MFS	17..452	CDD:119392	127/455 (28%)
Glut1	NP_612073.2	Sugar_tr	18..470	CDD:278511	134/470 (29%)
STP9	NP_175449.1	MFS_STP	31..477	CDD:340919	128/458 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100060
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810