DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Glut1 and AT1G19450

DIOPT Version :9

Sequence 1:	NP_612073.2	Gene:	Glut1 / 38109	FlyBaseID:	FBgn0264574	Length:	1440	Species:	Drosophila melanogaster
Sequence 2:	NP_173377.1	Gene:	AT1G19450 / 838529	AraportID:	AT1G19450	Length:	488	Species:	Arabidopsis thaliana

Alignment Length:	468	Identity:	157/468 - (33%)
Similarity:	245/468 - (52%)	Gaps:	45/468 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 IFSAVLGMLQFGYNTGVINAPEKNIENFMKDVYKDRYGEDISEEFIQQLYSVAVSIFAIGGMLGG 81
            :....||.:|||:..|..:..:..|   .||:     |..:||      |||..|:..:|.|:|.
plant    53 VLIVALGPIQFGFTCGYSSPTQAAI---TKDL-----GLTVSE------YSVFGSLSNVGAMVGA 103

  Fly    82 FSGGWMANRFGRKGGLLLNNVLGIAGACLMGFTKVSHSYEMLFLGRFIIGVNCGLNTSLVPMYIS 146
            .:.|.:|...||||.|::..:..|.|...:.|.|   ....|::||.:.|...|:.:..||:||:
plant   104 IASGQIAEYVGRKGSLMIAAIPNIIGWLSISFAK---DTSFLYMGRLLEGFGVGIISYTVPVYIA 165

  Fly   147 EIAPLNLRGGLGTVNQLAVTVGLLLSQVLGIEQILGTNEGWPILLGLAICPAILQLILLPVCPES 211
            ||||..:||.||:||||:||:|::|:.:||:      ...|.||..|.:.|..|.:..|...|||
plant   166 EIAPQTMRGALGSVNQLSVTIGIMLAYLLGL------FVPWRILAVLGVLPCTLLIPGLFFIPES 224

  Fly   212 PRYLL---ITKQWEEEARKALRRLRASGSVEEDIE-EMRAEERAQQSESHISTMELICSPTLRP- 271
            ||:|.   :|..:|    .:|:.||   ..|.||. |:...:|:..|.|..|.:..:.....|.
plant   225 PRWLAKMGLTDDFE----TSLQVLR---GFETDITVEVNEIKRSVASSSKRSAVRFVDLKRRRYY 282

  Fly   272 -PLIIGIVMQLSQQFSGINAVFYYSTSLFMSSGLTEESAKFATIGIGAIMVVMTLVSIPLMDRTG 335
             ||::||.:...||..|||.|.:||:::|.|:|:|  |:..||.|:|.:.||.|.::..|:|:.|
plant   283 FPLMVGIGLLALQQLGGINGVLFYSSTIFESAGVT--SSNVATFGVGVVQVVATGIATWLVDKAG 345

  Fly   336 RRTLHLYGLGGMFIFSIFITISFLIKE-------MIDWMSYLSVVATLGFVVFFAVGPGSIPWMI 393
            ||.|.:....||.|..:.:.::|.:||       |.:.:|.:|||..:..|:..::|.|.|||:|
plant   346 RRLLLMISSIGMTISLVIVAVAFYLKEFVSPDSNMYNILSMVSVVGVVAMVISCSLGMGPIPWLI 410

  Fly   394 TAELFSQGPRPSAMAIAVLVNWMANFVVGIGFPSMKTALENYTFLPFSVFLAIFWIFTYKKVPET 458
            .:|:.....:..|.:||.|:||..:::|.:....:.......||..:::......:|....||||
plant   411 MSEILPVNIKGLAGSIATLLNWFVSWLVTMTANMLLAWSSGGTFTLYALVCGFTVVFVSLWVPET 475

  Fly   459 KNKTFEEILALFR 471
            |.||.|||.||||
plant   476 KGKTLEEIQALFR 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Glut1	NP_612073.2	MFS	17..452	CDD:119392	143/447 (32%)
Glut1	NP_612073.2	Sugar_tr	18..470	CDD:278511	154/464 (33%)
AT1G19450	NP_173377.1	MFS_GLUT6_8_Class3_like	50..482	CDD:340916	150/460 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100060
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810