DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Glut1 and PMT5

DIOPT Version :9

Sequence 1:	NP_612073.2	Gene:	Glut1 / 38109	FlyBaseID:	FBgn0264574	Length:	1440	Species:	Drosophila melanogaster
Sequence 2:	NP_188513.1	Gene:	PMT5 / 821416	AraportID:	AT3G18830	Length:	539	Species:	Arabidopsis thaliana

Alignment Length:	505	Identity:	132/505 - (26%)
Similarity:	233/505 - (46%)	Gaps:	61/505 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 AFLCAPGLTFFLTYSIFSAVLGMLQFGYNTGVINAPEKNIENFMKDVYKDRYGEDISEEFIQQLY 66
            ||.||          |.:::..:| .||:.||::.....|:..:|                  :.
plant    36 AFACA----------ILASMTSIL-LGYDIGVMSGAMIYIKRDLK------------------IN 71

  Fly    67 SVAVSIFA----IGGMLGGFSGGWMANRFGRKGGLLLNNVLGIAGACLMGFTKVSHSYEMLFLGR 127
            .:.:.|.|    |..::|..:.|..::..||:..::|...:..|||.|||   :|.:|..|..||
plant    72 DLQIGILAGSLNIYSLIGSCAAGRTSDWIGRRYTIVLAGAIFFAGAILMG---LSPNYAFLMFGR 133

  Fly   128 FIIGVNCGLNTSLVPMYISEIAPLNLRGGLGTVNQLAVTVGLLLSQVLGIE-QILGTNEGWPILL 191
            ||.|:..|....:.|:|.:|::|.:.||.|.:..::.:..|::|..|..:. ..|....||.::|
plant   134 FIAGIGVGYALMIAPVYTAEVSPASSRGFLNSFPEVFINAGIMLGYVSNLAFSNLPLKVGWRLML 198

  Fly   192 GLAICPAILQLILLPVCPESPRYLLI-------------TKQWEEEARKALRRLRASGSVEEDIE 243
            |:...|:::..|.:...|||||:|::             |.....||...|..::.:..:..|..
plant   199 GIGAVPSVILAIGVLAMPESPRWLVMQGRLGDAKRVLDKTSDSPTEATLRLEDIKHAAGIPADCH 263

  Fly   244 EMRAEERAQQSESHISTMELICSPT--LRPPLIIGIVMQLSQQFSGINAVFYYSTSLFMSSGL-T 305
            :...:...:.|.......||:..||  :|..:|..|.:...||.|||:||..:|..:|.::|| |
plant   264 DDVVQVSRRNSHGEGVWRELLIRPTPAVRRVMIAAIGIHFFQQASGIDAVVLFSPRIFKTAGLKT 328

  Fly   306 EESAKFATIGIGAIMVVMTLVSIPLMDRTGRRTLHLYGLGGMFI----FSIFITISFLIKEMIDW 366
            :.....||:.:|.:.....||:..|:||.|||.|.|..:|||.:    ....:||....::.:.|
plant   329 DHQQLLATVAVGVVKTSFILVATFLLDRIGRRPLLLTSVGGMVLSLAALGTSLTIIDQSEKKVMW 393

  Fly   367 MSYLSVVATLGFVVFFAVGPGSIPWMITAELFSQGPRPSAMAIAVLVNWMANFVVGIGF-PSMKT 430
            ...:::...:.:|..|::|.|.|.|:.::|:|....|....::.|:||.:.:.|:.|.| |..|.
plant   394 AVVVAIATVMTYVATFSIGAGPITWVYSSEIFPLRLRSQGSSMGVVVNRVTSGVISISFLPMSKA 458

  Fly   431 ALENYTFLPFSVFLAIFWIFTYKKVPETKNKTFE---EILALFRHNNGRS 477
            ......|..|.....:.|:|.|..:|||:.:..|   |:.:.||..:.:|
plant   459 MTTGGAFYLFGGIATVAWVFFYTFLPETQGRMLEDMDELFSGFRWRDSKS 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Glut1	NP_612073.2	MFS	17..452	CDD:119392	119/460 (26%)
Glut1	NP_612073.2	Sugar_tr	18..470	CDD:278511	124/480 (26%)
PMT5	NP_188513.1	MFS_PLT	42..494	CDD:340995	123/473 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D326501at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920