DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Glut1 and AT2G18480

DIOPT Version :9

Sequence 1:	NP_612073.2	Gene:	Glut1 / 38109	FlyBaseID:	FBgn0264574	Length:	1440	Species:	Drosophila melanogaster
Sequence 2:	NP_179438.1	Gene:	AT2G18480 / 816363	AraportID:	AT2G18480	Length:	508	Species:	Arabidopsis thaliana

Alignment Length:	495	Identity:	140/495 - (28%)
Similarity:	240/495 - (48%)	Gaps:	59/495 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 AFLCAPGLTFFLTYSIFSAVLGMLQFGYNTGVINAPEKNIENFMKDVYKDRYGEDISEEFIQQLY 66
            ||.||      :..||.|.:     |||:|||::    ..:.|::|..|      |::..|:
plant    22 AFGCA------IVASIISII-----FGYDTGVMS----GAQIFIRDDLK------INDTQIE--- 62

  Fly    67 SVAVSIFAIGGMLGGFSGGWMANRFGRKGGLLLNNVLGIAGACLMGFTKVSHSYEMLFLGRFIIG 131
             |...|..:..::|..:.|..::..||:..:.|:.|:.:.|:.|||:   ..:|.:|.:||.|.|
plant    63 -VLAGILNLCALVGSLTAGKTSDVIGRRYTIALSAVIFLVGSVLMGY---GPNYPVLMVGRCIAG 123

  Fly   132 VNCGLNTSLVPMYISEIAPLNLRGGLGTVNQLAVTVGLLLSQV----LGIEQILGTNEGWPILLG 192
            |..|....:.|:|.:||:..:.||.|.::.:|.:::|:||..|    .|   .|....||.::||
plant   124 VGVGFALMIAPVYSAEISSASHRGFLTSLPELCISLGILLGYVSNYCFG---KLTLKLGWRLMLG 185

  Fly   193 LAICPAILQLILLPVCPESPRYL-------------LITKQWEEEARKALRRLRASGSVEEDIEE 244
            :|..|:::....:...|||||:|             ::....||||.:..|.:..:..|  |:.|
plant   186 IAAFPSLILAFGITRMPESPRWLVMQGRLEEAKKIMVLVSNTEEEAEERFRDILTAAEV--DVTE 248

  Fly   245 MRAEERAQQSESHISTM--ELICS--PTLRPPLIIGIVMQLSQQFSGINAVFYYSTSLFMSSG-L 304
            ::......:.::|..::  ||:..  |.:|..||..:.:...:..:||.||..||..:|..:| :
plant   249 IKEVGGGVKKKNHGKSVWRELVIKPRPAVRLILIAAVGIHFFEHATGIEAVVLYSPRIFKKAGVV 313

  Fly   305 TEESAKFATIGIGAIMVVMTLVSIPLMDRTGRRTLHLYGLGGMFIFSIFITISFLIKE---MIDW 366
            :::....||:|:|.......:::..|:|:.|||.|.|...|||......:.:|..:.:   .:.|
plant   314 SKDKLLLATVGVGLTKAFFIIIATFLLDKVGRRKLLLTSTGGMVFALTSLAVSLTMVQRFGRLAW 378

  Fly   367 MSYLSVVATLGFVVFFAVGPGSIPWMITAELFSQGPRPSAMAIAVLVNWMANFVVGIGFPSMKTA 431
            ...||:|:|..||.||::|.|.|.|:.::|:|....|....:|.|.||.:.|..|.:.|.||..|
plant   379 ALSLSIVSTYAFVAFFSIGLGPITWVYSSEIFPLRLRAQGASIGVAVNRIMNATVSMSFLSMTKA 443

  Fly   432 L-ENYTFLPFSVFLAIFWIFTYKKVPETKNKTFEEILALF 470
            : ....|..|:......|.|.:..:||||....||:..||
plant   444 ITTGGVFFVFAGIAVAAWWFFFFMLPETKGLPLEEMEKLF 483

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Glut1	NP_612073.2	MFS	17..452	CDD:119392	127/460 (28%)
Glut1	NP_612073.2	Sugar_tr	18..470	CDD:278511	132/477 (28%)
AT2G18480	NP_179438.1	MFS_PLT	36..479	CDD:340995	130/464 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910