Protein Alignment Glut1 and SLC2A10

DIOPT Version :9

• Sequence 1: NP_612073.2
• Gene: Glut1 / 38109
• FlyBaseID: FBgn0264574
• Length: 1440
• Species: Drosophila melanogaster
• Sequence 2: XP_011527362.1
• Gene: SLC2A10 / 81031
• HGNCID: 13444
• Length: 562
• Species: Homo sapiens
• Alignment Length: 574
• Identity: 136/574 - (23%)
• Similarity: 235/574 - (40%)
• Gaps: 141/574 - (24%)

  Fly    20 AVLGMLQFGYNTGVINAPEKNIENFMKDVYKDRYGEDISEEFIQQLYSVAVSIFAIGGMLGGFSG 84
            ::||.|.|||...||:..       :..:..|.....:.:||:       |....:|.:|....|
Human    36 SLLGGLTFGYELAVISGA-------LLPLQLDFGLSCLEQEFL-------VGSLLLGALLASLVG 86

  Fly    85 GWMANRFGRKGGLLLNNVLGIAGACLMGFTKVSHSYEMLFLGRFIIGVNCGLNTSLVPMYISEIA 149
            |::.:.:|||..:|.:|::.:||:..:|   ::.|...|.|||.::|....|::....:|:||:.
Human    87 GFLIDCYGRKQAILGSNLVLLAGSLTLG---LAGSLAWLVLGRAVVGFAISLSSMACCIYVSELV 148

  Fly   150 PLNLRGGLGTVNQLAVTVGLLLSQVLGIEQILGTNEGWPILLGLAICPAILQ---LILLPV-CPE 210
            ....||.|.::.:..:|||:|||..|.. .:.||..||..:.|.|..||:||   |:.||. ..|
Human   149 GPRQRGVLVSLYEAGITVGILLSYALNY-ALAGTPWGWRHMFGWATAPAVLQSLSLLFLPAGTDE 212

  Fly   211 SPRYL-LITKQWEEEARKALRRLRASGSVEEDIEEMRAEERAQQSESHISTMELICSPTLRPPLI 274
            :..:. ||..|..|..:....|.|.|     .::..||.:                  .:|....
Human   213 TATHKDLIPLQGGEAPKLGPGRPRYS-----FLDLFRARD------------------NMRGRTT 254

  Fly   275 IGIVMQLSQQFSGINAVFYYSTSLFMSSGL-TEESAKFATIGIGAIMVVMTLVSIPLMDRTGRRT 338
            :|:.:.|.||.:|...|..|::::|.|.|. ...||..|::|:||:.|..||.::.|:||.|||.
Human   255 VGLGLVLFQQLTGQPNVLCYASTIFSSVGFHGGSSAVLASVGLGAVKVAATLTAMGLVDRAGRRA 319

  Fly   339 LHLYG-------LGGMFIFSIFITI---------------------SFLIKE------------- 362
            |.|.|       :.|:.:.|..:.:                     |.|:::
Human   320 LLLAGCALMALSVSGIGLVSFAVPMDSGPSCLAVPNATGQTGLPGDSGLLQDSSLPPIPRTNEDQ 384

  Fly   363 -------------------------------------------MIDWMSYLSVVATLGFVVFFAV 384
                                                       ::.|.:.|.::.   ||..|:.
Human   385 REPILSTAKKTKPHPRSGDPSAPPRLALSSALPGPPLPARGHALLRWTALLCLMV---FVSAFSF 446

  Fly   385 GPGSIPWMITAELFSQGPRPSAMAIAVLVNWMANFVVGIGFPSM-KTALENYTFLPFSVFLAIFW 448
            |.|.:.|::.:|::....|..|.|.....||.||..:.:.|..: .|...::|||.:.:...:..
Human   447 GFGPVTWLVLSEIYPVEIRGRAFAFCNSFNWAANLFISLSFLDLIGTIGLSWTFLLYGLTAVLGL 511

  Fly   449 IFTYKKVPETKNKTFEEILALFRHNNGRSMLNCTNSLEPQSMNSGIEHAALMVS 502
            .|.|..|||||.::..||...|:..      ..|.|...:..::||.::.:.:|
Human   512 GFIYLFVPETKGQSLAEIDQQFQKR------RFTLSFGHRQNSTGIPYSRIEIS 559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glut1	NP_612073.2	MFS	17..452	CDD:119392	122/522 (23%)
		Sugar_tr	18..470	CDD:278511	130/540 (24%)
SLC2A10	XP_011527362.1	Sugar_tr	32..533	CDD:278511	130/540 (24%)
		MFS	35..518	CDD:119392	123/525 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D326501at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.010