Protein Alignment Glut1 and SLC2A11

DIOPT Version :9

• Sequence 1: NP_612073.2
• Gene: Glut1 / 38109
• FlyBaseID: FBgn0264574
• Length: 1440
• Species: Drosophila melanogaster
• Sequence 2: NP_001269793.1
• Gene: SLC2A11 / 66035
• HGNCID: 14239
• Length: 535
• Species: Homo sapiens
• Alignment Length: 489
• Identity: 149/489 - (30%)
• Similarity: 249/489 - (50%)
• Gaps: 41/489 - (8%)

  Fly     4 LCAPGLTFFLTYSIFSAVLGMLQFGYNTGVINAPEKNIENFMKDVYKDRYGEDISEEFIQQLYSV 68
            :||.|:.            |..|||||..:||||..:|:.|..:.::.|.||.:.:..:..::|:
Human    24 ICAAGIG------------GTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVLLMWSL 76

  Fly    69 AVSIFAIGGMLGGFSGGWMANRFGRKGGLLLNNVLGIAGACLMGFTKVSHSYEMLFLGRFIIGVN 133
            .||::.:||:.|....|.:|...|||..||:||:..::.|.|.||::.:.|:||:.|||.::|||
Human    77 IVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVGVN 141

  Fly   134 CGLNTSLVPMYISEIAPLNLRGGLGTVNQLAVTVGLLLSQVLGIEQILGTNEGWPILLGLAICPA 198
            .|::.::.|||:.|.||..|||.:...:.:...:|:::.||:|:.::||..:.||:||...:.|.
Human   142 AGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWPLLLASCLVPG 206

  Fly   199 ILQLILLPVCPESPRYLLITKQWEEEARKALRRLRASGSVEEDIEEMRAEERAQQSESHISTMEL 263
            .|||..||:.|||||||||.....|....||||||.||.:..::||:..|..|.|........||
Human   207 ALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEELEEERAACQGCRARRPWEL 271

  Fly   264 ICSPTLRPPLIIGIVMQLSQQFSGINAVFYYSTSLFMSSGLTEESAKFATIGIGAIMVVMTLVSI 328
            .....||..:...:|:..:.:..|.::|:.|::|:|..:|:.|...::|.||.|:..::..:||:
Human   272 FQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVPEAKIQYAIIGTGSCELLTAVVSV 336

  Fly   329 PLMDRTGRRTLHLYGLGGMFIFSIFITISFLIKEMIDWMSYLSVVATLGFVVFFAVGPGSIPWMI 393
            ..:|.         |.|.....:.........:....|..||::.....|::.|.:||..:..::
Human   337 AGVDE---------GWGVQAGLTSTSPPPRPRQSSFPWTLYLAMACIFAFILSFGIGPAGVTGIL 392

  Fly   394 TAELFSQGPRPSAMAIAVLVNWMANFVVGIGFPSMKTALENYTFLPFSVFLAIFWIFTYKKVPET 458
            ..|||.|..||:|..:...:.|:...:||:|||                |:.:...|..::.|
Human   393 ATELFDQMARPAACMVCGALMWIMLILVGLGFP----------------FIMVLGSFLIRRRP-- 439

  Fly   459 KNKTFEEILALFRHNNGRSMLNCTNSLEPQSMNS 492
             ..|....|:|...:.|.|.|.| :.|.|::..|
Human   440 -CPTSSMSLSLVSVSVGPSTLAC-SFLRPKARPS 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glut1	NP_612073.2	MFS	17..452	CDD:119392	135/434 (31%)
		Sugar_tr	18..470	CDD:278511	138/451 (31%)
SLC2A11	NP_001269793.1	Sugar_tr	22..428	CDD:278511	137/440 (31%)
		MFS	68..>217	CDD:119392	54/148 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0569
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D291809at33208
OrthoFinder	1	1.000	-	-		FOG0000120
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23503
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.920