back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Glut1 and SLC2A4

DIOPT Version :9

Sequence 1:	NP_612073.2	Gene:	Glut1 / 38109	FlyBaseID:	FBgn0264574	Length:	1440	Species:	Drosophila melanogaster
Sequence 2:	NP_001033.1	Gene:	SLC2A4 / 6517	HGNCID:	11009	Length:	509	Species:	Homo sapiens

Alignment Length:	491	Identity:	244/491 - (49%)
Similarity:	333/491 - (67%)	Gaps:	15/491 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LTFFLTYSIFSAVLGMLQFGYNTGVINAPEKNIENFMKDVYKDRYGED----ISEEFIQQLYSVA 69
            :|..|..::||||||.||||||.||||||:|.||....:.:..|.|.:    |....:..|::::
Human    20 VTGTLVLAVFSAVLGSLQFGYNIGVINAPQKVIEQSYNETWLGRQGPEGPSSIPPGTLTTLWALS 84

  Fly    70 VSIFAIGGMLGGFSGGWMANRFGRKGGLLLNNVLGIAGACLMGFTKVSHSYEMLFLGRFIIGVNC 134
            |:||::|||:..|..|.::...|||..:|:||||.:.|..|||....:.|||||.||||:||...
Human    85 VAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAASYEMLILGRFLIGAYS 149

  Fly   135 GLNTSLVPMYISEIAPLNLRGGLGTVNQLAVTVGLLLSQVLGIEQILGTNEGWPILLGLAICPAI 199
            ||.:.|||||:.||||.:|||.|||:||||:.:|:|::||||:|.:|||...||:||||.:.||:
Human   150 GLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVLGLESLLGTASLWPLLLGLTVLPAL 214

  Fly   200 LQLILLPVCPESPRYLLITKQWEEEARKALRRLRASGSVEEDIEEMRAEERAQQSESHISTMELI 264
            |||:|||.||||||||.|.:..|..|||:|:||.....|...:.|::.|:|..:.|..:|.::|:
Human   215 LQLVLLPFCPESPRYLYIIQNLEGPARKSLKRLTGWADVSGVLAELKDEKRKLERERPLSLLQLL 279

  Fly   265 CSPTLRPPLIIGIVMQLSQQFSGINAVFYYSTSLFMSSGLTEESAKFATIGIGAIMVVMTLVSIP 329
            .|.|.|.||||.:|:|||||.||||||||||||:|.::|:.:.:  :||||.|.:..|.||||:.
Human   280 GSRTHRQPLIIAVVLQLSQQLSGINAVFYYSTSIFETAGVGQPA--YATIGAGVVNTVFTLVSVL 342

  Fly   330 LMDRTGRRTLHLYGLGGMFIFSIFITISFLIKEMIDWMSYLSVVATLGFVVFFAVGPGSIPWMIT 394
            |::|.|||||||.||.||...:|.:|::.|:.|.:..|||:|:||..|||.||.:|||.|||.|.
Human   343 LVERAGRRTLHLLGLAGMCGCAILMTVALLLLERVPAMSYVSIVAIFGFVAFFEIGPGPIPWFIV 407

  Fly   395 AELFSQGPRPSAMAIAVLVNWMANFVVGIGFPSMKTALENYTFLPFSVFLAIFWIFTYKKVPETK 459
            ||||||||||:|||:|...||.:||::|:||..:..|:..|.||.|:|.|..|:|||:.:||||:
Human   408 AELFSQGPRPAAMAVAGFSNWTSNFIIGMGFQYVAEAMGPYVFLLFAVLLLGFFIFTFLRVPETR 472

  Fly   460 NKTFEEILALFRHNNGRSMLNCTNSLEPQSMNSGIE 495
            .:||::|.|.|..         |.||..|.:....|
Human   473 GRTFDQISAAFHR---------TPSLLEQEVKPSTE 499

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.