Protein Alignment Glut1 and Slc33a1

DIOPT Version :10

• Sequence 1: NP_612073.2
• Gene: Glut1 / 38109
• FlyBaseID: FBgn0264574
• Length: 1440
• Species: Drosophila melanogaster
• Sequence 2: NP_071588.2
• Gene: Slc33a1 / 64018
• RGDID: 620653
• Length: 550
• Species: Rattus norvegicus
• Alignment Length: 439
• Identity: 89/439 - (20%)
• Similarity: 168/439 - (38%)
• Gaps: 128/439 - (29%)

  Fly    60 EFIQQLYSVAVSIFAIGGMLGGFSGGWMA--NRFGRKGGLLLNNVLGI----AGAC--LMGFTK- 115
            ||:.....:||..:|: .||...:.|:.:  |..|:..|..|.|||.:    |..|  .:.|..
  Rat   187 EFLAATQDIAVDGWAL-TMLSRENVGYASTCNSVGQTAGYFLGNVLFLALESADFCNKYLRFQPQ 250

  Fly   116 ----VSHSYEMLFLGRFIIGVNCGLNTSLVPMYISEIAPLNLRGGLGTVNQLAVTVGLLLSQVLG 176
                |:.|..:.|.|...:     :.|:||.:...|            ..:.:|..
  Rat   251 PRGIVTLSDFLFFWGTVFL-----ITTTLVALLKKE------------TREASVVK--------- 289

  Fly   177 IEQILGTNEGWPILLGLAICPAILQLILLPVCPESPRYLLITKQWEEEARKALRRLRASGSVEED 241
             |:..|..:.:.:|..:...||:|...|          |::|.:....|..|:..|:.   |||.
  Rat   290 -EETQGITDTYKLLFSIIKMPAVLAFCL----------LILTSKIGFSAADAVTGLKL---VEEG 340

  Fly   242 IEEMRAEERAQQSESHISTMELICSPTLRPPLIIGIVMQLSQQFSG---INAVFYYSTSLFMSSG 303
            :           .:.|::   |:..|.:  ||.|.:.:.:|:..:|   :| :||.:....:..|
  Rat   341 V-----------PKEHLA---LLAVPMV--PLQIILPLLISKYTAGPQPLN-IFYKAMPYRLLLG 388

  Fly   304 LTEESAKFATIGIGAIMVVMTLVSIPLMDRTGRRTLHL-------YGLGGMFIFSIFITISFLIK 361
            |..           |::|..|    |.::..|...::.       |.|..:.::|::::|.....
  Rat   389 LEY-----------ALLVWWT----PKVEHQGGFPIYYYIIVLLSYALHQVTLYSMYVSIMAFNA 438

  Fly   362 EMID------WMSYLSVVATLG-----FVVFFAVGPGSIPWMITAELFSQGPR-PSAMAIAVLVN 414
            ::.|      :|:.|:.|:.||     .|..:.|.|.::...:.|.  :|..| |.|:.:...:.
  Rat   439 KVSDPLIGGTYMTLLNTVSNLGGNWPSTVALWLVDPLTVKECVGAS--NQNCRTPEAIELCKKLG 501

  Fly   415 WMANFVVGIGFPSMKTALENYTFLPFSVFLAI---FWIF---TYKKVPE 457
                       .|..|||:.| ::...|.:.|   :|.|   .:||:.:
  Rat   502 -----------GSCVTALDGY-YVESIVCVLIGFGWWFFLGPKFKKLQD 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glut1	NP_612073.2	MFS_GLUT_Class1	15..461	CDD:340989	89/439 (20%)
Slc33a1	NP_071588.2	2A0125	86..459	CDD:273329	68/344 (20%)