DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Glut1 and CG3285

DIOPT Version :9

Sequence 1:	NP_612073.2	Gene:	Glut1 / 38109	FlyBaseID:	FBgn0264574	Length:	1440	Species:	Drosophila melanogaster
Sequence 2:	NP_001285583.1	Gene:	CG3285 / 33547	FlyBaseID:	FBgn0031522	Length:	466	Species:	Drosophila melanogaster

Alignment Length:	503	Identity:	122/503 - (24%)
Similarity:	211/503 - (41%)	Gaps:	105/503 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 IFSAVLGMLQFGYNTGVINAPEKNIENFMKDVYKDRYGEDISEEF---IQQLYSVAVSIFAIGGM 78
            :.:.:|.:..|.:..||         .:|..|.:|...::...:|   :.|:..:. |:..||.:
  Fly    27 LVTLLLNIATFSHGLGV---------GWMSPVMRDLQTDESPLDFPVLVSQVSWIG-SLVGIGSV 81

  Fly    79 LGGFSGGWMANRFGRKGGLLLNNVLGIAGACLMGFTKVSHSYEMLFLGRFIIGVNCGLNTSLVPM 143
            :|....|.:.:|.|||..|....:......||:.|.:   |.|.|::||.:.|:..|....::|.
  Fly    82 MGNLIAGLLMDRIGRKMVLFFIAIPYTTFWCLIYFVQ---SVEFLYIGRLMAGITGGACYVVLPT 143

  Fly   144 YISEIAPLNLRGGLGTVNQLAVTVGLLLSQVLGIEQILGTNEGWPILLGLAICPAILQLILLPVC 208
            :|||||..|:||.||::..|:|..|:|...::.......|:.  |.::||.:|..|...::
  Fly   144 FISEIADTNVRGRLGSIILLSVNTGVLAGYIVSTRVDYFTSP--PFIIGLPVCYFICNFLI---- 202

  Fly   209 PESPRYLLITKQWEEEARKAL--RRLRASG-SVEEDIEEMR---AEERAQQSESHISTMELICSP 267
            ||:|.:|:...::|...|..:  :.:|.:. ..|::.|||:   .:|:.::::| ....:.|..|
  Fly   203 PETPHHLVRKGKFEAAKRSFMFYKNIRKNDIKAEDEFEEMKYLLIKEQTEKAKS-FDYRDFITRP 266

  Fly   268 TLRPPLIIGIVMQLSQQFSGINAVFYYSTSLFMSSGLTEESAKFATIGIGAIMVVMTLVSIPLMD 332
            ..: ......|:.:|.|||....|..|...:|.:|. |..:....||.||.:.:|...|:..|.|
  Fly   267 AFK-AYASAAVLLISNQFSASFCVTTYLADVFAASH-TTLNLGMCTIIIGVLQIVGNYVTTLLCD 329

  Fly   333 RTGRRTLHLYG-LGGMFIFSIFITISFLIK----EMIDWMS--------YLSVVATLG--FVVFF 382
            :.|||.|.|.. ||.....:.|.|.:|..:    ..:||:.        :|..:..:|  |||..
  Fly   330 KYGRRILMLTSTLGASVCLTAFGTFTFFAEAADLSSVDWLPLVILSCFVFLCNIGLVGCLFVVLV 394

  Fly   383 AVGPGSI--------------PWMITAELFSQGPRPSAMAI--AVLVNWMANFVVGIGFPSMKTA 431
            .:.|..|              ...:|.::|     |..||:  ..:..|..:   ||.|
  Fly   395 ELFPAKIRSVSVSTFVVILSSTVFLTLKIF-----PICMAVWGTSVTMWSCS---GITF------ 445

  Fly   432 LENYTFLPFSVFLAIFWIFTYKKVPETKNKTFEEILALFRHNNGRSML 479
               ::||.|..||                   ||       .||:|:|
  Fly   446 ---FSFLYFCFFL-------------------EE-------TNGKSLL 464

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Glut1	NP_612073.2	MFS	17..452	CDD:119392	116/474 (24%)
Glut1	NP_612073.2	Sugar_tr	18..470	CDD:278511	118/491 (24%)
CG3285	NP_001285583.1	MFS	29..443	CDD:119392	108/443 (24%)
CG3285	NP_001285583.1	MFS_1	32..419	CDD:284993	102/408 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
	2	1.910