Protein Alignment Glut1 and slc2a2

DIOPT Version :10

• Sequence 1: NP_612073.2
• Gene: Glut1 / 38109
• FlyBaseID: FBgn0264574
• Length: 1440
• Species: Drosophila melanogaster
• Sequence 2: NP_001036186.1
• Gene: slc2a2 / 322493
• ZFINID: ZDB-GENE-030131-1213
• Length: 504
• Species: Danio rerio
• Alignment Length: 480
• Identity: 216/480 - (45%)
• Similarity: 314/480 - (65%)
• Gaps: 15/480 - (3%)

  Fly     9 LTFFLTYSIFSAVLGMLQFGYNTGVINAPEKNIEN--------FMKDVYKDRYG-----EDISEE 60
            ||..|..::|:|.||.||.||:.||||||:|.||.        :.:|:.:...|     |..::.
Zfish     5 LTGTLALAVFTAALGSLQMGYSLGVINAPQKVIERHYARSLGVYNEDLARSEGGNGTEHEKPTDP 69

  Fly    61 FIQQLYSVAVSIFAIGGMLGGFSGGWMANRFGRKGGLLLNNVLGIAGACLMGFTKVSHSYEMLFL 125
            .:...:|::|:||::||||..|...::.:..||..|:|..|||.|....|||..|:...:.|:..
Zfish    70 SVVMYWSLSVAIFSVGGMLSSFLVSFVGDFRGRIKGMLAINVLAITAGLLMGLAKMGTPHLMVIA 134

  Fly   126 GRFIIGVNCGLNTSLVPMYISEIAPLNLRGGLGTVNQLAVTVGLLLSQVLGIEQILGTNEGWPIL 190
            ||.|:|:.|||::.|||:||.||:|:..||.:|.::|||:.:|:|:|||:|::.:||.:..|.||
Zfish   135 GRAIMGLYCGLSSGLVPLYIGEISPVKYRGAMGALHQLAIVIGILISQVIGLDFLLGNDYMWHIL 199

  Fly   191 LGLAICPAILQLILLPVCPESPRYLLITKQWEEEARKALRRLRASGSVEEDIEEMRAEERAQQSE 255
            |||:..|||||.:||.|||||||||.|.:...|:|.|:|:||:......:||.||:||:.....|
Zfish   200 LGLSGAPAILQSLLLLVCPESPRYLYIKQGKVEDACKSLKRLKGDYDTSKDIAEMKAEKEEAMKE 264

  Fly   256 SHISTMELICSPTLRPPLIIGIVMQLSQQFSGINAVFYYSTSLFMSSGLTEESAKFATIGIGAIM 320
            :.:|.:.|:.|...|..|.:.::|..|||||||||:||||||:|.::|:.:  ..:||||:|.:.
Zfish   265 AKMSILRLLRSSVYRQQLFVALMMHFSQQFSGINAIFYYSTSIFQTAGVGQ--PVYATIGVGVVN 327

  Fly   321 VVMTLVSIPLMDRTGRRTLHLYGLGGMFIFSIFITISFLIKEMIDWMSYLSVVATLGFVVFFAVG 385
            ::.||||:.::||.|||||.|.|||||...::.:|:....:....||||:|:||...||.||.:|
Zfish   328 IIFTLVSVLMVDRAGRRTLTLVGLGGMCCCAVAMTVGLAFQGAYSWMSYVSMVAIFMFVSFFEIG 392

  Fly   386 PGSIPWMITAELFSQGPRPSAMAIAVLVNWMANFVVGIGFPSMKTALENYTFLPFSVFLAIFWIF 450
            ||.|||.|.||:|||||||:|:|:|...||..||:||:.||.:.:...:|.|:.|:|.|..|.:|
Zfish   393 PGPIPWFIVAEIFSQGPRPAAIALAGFCNWTCNFIVGMVFPYLVSLCGSYVFIVFAVLLFGFTLF 457

  Fly   451 TYKKVPETKNKTFEEILALFRHNNG 475
            .|.:|||||.||||||.|:|...:|
Zfish   458 IYFRVPETKGKTFEEIAAVFHRKHG 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glut1	NP_612073.2	MFS_GLUT_Class1	15..461	CDD:340989	204/458 (45%)
slc2a2	NP_001036186.1	MFS_GLUT_Class1	11..468	CDD:340989	204/458 (45%)