Protein Alignment Glut1 and Slc2a3

DIOPT Version :10

• Sequence 1: NP_612073.2
• Gene: Glut1 / 38109
• FlyBaseID: FBgn0264574
• Length: 1440
• Species: Drosophila melanogaster
• Sequence 2: NP_001399481.1
• Gene: Slc2a3 / 25551
• RGDID: 3706
• Length: 495
• Species: Rattus norvegicus
• Alignment Length: 490
• Identity: 245/490 - (50%)
• Similarity: 333/490 - (67%)
• Gaps: 9/490 - (1%)

  Fly     7 PGLTFFLTYSIFSAVLGMLQFGYNTGVINAPEKNIENFMKDVYKDRYGEDISEEFIQQLYSVAVS 71
            |.|.|.:|.    |.:|..|||||||||||||..|::|:....::|..:..||..:..|:|:.|:
  Rat    10 PSLVFAVTV----ATIGSFQFGYNTGVINAPETIIKDFLNYTLEERLEDLPSEGLLTTLWSLCVA 70

  Fly    72 IFAIGGMLGGFSGGWMANRFGRKGGLLLNNVLGIAGACLMGFTKVSHSYEMLFLGRFIIGVNCGL 136
            ||::|||:|.||.|...|||||:..:||.|::.|.|.|||||.|::.|.|||.|||.|||:.|||
  Rat    71 IFSVGGMIGSFSVGLFVNRFGRRNSMLLVNLIAILGGCLMGFAKIAESVEMLILGRLIIGIFCGL 135

  Fly   137 NTSLVPMYISEIAPLNLRGGLGTVNQLAVTVGLLLSQVLGIEQILGTNEGWPILLGLAICPAILQ 201
            .|..|||||.|::|..|||..||:|||.:.||:|::||.|::.|||:.|.||.||||.|.|||||
  Rat   136 CTGFVPMYIGEVSPTALRGAFGTLNQLGIVVGILVAQVFGLDFILGSEELWPGLLGLTIIPAILQ 200

  Fly   202 LILLPVCPESPRYLLITKQWEEEARKALRRLRASGSVEEDIEEMRAEERAQQSESHISTMELICS 266
            ...||.||||||:|||.::.|::|.:.|:||..:..|.::|:||:.|......|..::.:||..|
  Rat   201 SAALPFCPESPRFLLINRKEEDQATEILQRLWGTPDVIQEIQEMKDESIRMSQEKQVTVLELFKS 265

  Fly   267 PTLRPPLIIGIVMQLSQQFSGINAVFYYSTSLFMSSGLTEESAKFATIGIGAIMVVMTLVSIPLM 331
            |:...||:|.:|:|||||||||||||||||.:|..:|:.|..  :||||.|.:..:.|:||:.|:
  Rat   266 PSYFQPLLISVVLQLSQQFSGINAVFYYSTGIFQDAGVQEPI--YATIGAGVVNTIFTVVSLFLV 328

  Fly   332 DRTGRRTLHLYGLGGMFIFSIFITISFLIKEMIDWMSYLSVVATLGFVVFFAVGPGSIPWMITAE 396
            :|.||||||:.|||||.:.|:|:|||.|:|:..:.||::.:||.|.:|.||.:|||.|||.|.||
  Rat   329 ERAGRRTLHMIGLGGMAVCSVFMTISLLLKDEYEAMSFVCIVAILVYVAFFEIGPGPIPWFIVAE 393

  Fly   397 LFSQGPRPSAMAIAVLVNWMANFVVGIGFPSMKTALENYTFLPFSVFLAIFWIFTYKKVPETKNK 461
            ||||||||:|||:|...||.:||:||:.|||....|..|.|:.|:.||..|.|||:.||||||.:
  Rat   394 LFSQGPRPAAMAVAGCSNWTSNFLVGMFFPSAAAYLGAYVFIIFAAFLVFFLIFTFFKVPETKGR 458

  Fly   462 TFEEILALF--RHNNGRSMLNC-TNSLEPQSMNSG 493
            |||:|...|  :..:|:..... .||::|.....|
  Rat   459 TFEDITRAFEGQAQSGKGSAGVELNSMQPVKETPG 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glut1	NP_612073.2	MFS_GLUT_Class1	15..461	CDD:340989	231/445 (52%)
Slc2a3	NP_001399481.1	MFS_GLUT_Class1	14..458	CDD:340989	233/449 (52%)