Protein Alignment Glut1 and Slc2a3

DIOPT Version :10

• Sequence 1: NP_612073.2
• Gene: Glut1 / 38109
• FlyBaseID: FBgn0264574
• Length: 1440
• Species: Drosophila melanogaster
• Sequence 2: NP_001397304.1
• Gene: Slc2a3 / 20527
• MGIID: 95757
• Length: 495
• Species: Mus musculus
• Alignment Length: 490
• Identity: 242/490 - (49%)
• Similarity: 331/490 - (67%)
• Gaps: 9/490 - (1%)

  Fly     7 PGLTFFLTYSIFSAVLGMLQFGYNTGVINAPEKNIENFMKDVYKDRYGEDISEEFIQQLYSVAVS 71
            |.|.|.:|.    |.:|..|||||||||||||..:::|:....::|..:..||..:..|:|:.|:
Mouse    10 PSLVFAVTV----ATIGSFQFGYNTGVINAPETILKDFLNYTLEERLEDLPSEGLLTALWSLCVA 70

  Fly    72 IFAIGGMLGGFSGGWMANRFGRKGGLLLNNVLGIAGACLMGFTKVSHSYEMLFLGRFIIGVNCGL 136
            ||::|||:|.||.|...|||||:..:||.|:|.|...|||||.|::.|.|||.|||.:||:.|||
Mouse    71 IFSVGGMIGSFSVGLFVNRFGRRNSMLLVNLLAIIAGCLMGFAKIAESVEMLILGRLLIGIFCGL 135

  Fly   137 NTSLVPMYISEIAPLNLRGGLGTVNQLAVTVGLLLSQVLGIEQILGTNEGWPILLGLAICPAILQ 201
            .|..|||||.|::|..|||..||:|||.:.||:|::|:.|::.|||:.|.||.||||.|.|||||
Mouse   136 CTGFVPMYIGEVSPTALRGAFGTLNQLGIVVGILVAQIFGLDFILGSEELWPGLLGLTIIPAILQ 200

  Fly   202 LILLPVCPESPRYLLITKQWEEEARKALRRLRASGSVEEDIEEMRAEERAQQSESHISTMELICS 266
            ...||.||||||:|||.|:.|::|.:.|:||..:..|.::|:||:.|......|..::.:||..|
Mouse   201 SAALPFCPESPRFLLINKKEEDQATEILQRLWGTSDVVQEIQEMKDESVRMSQEKQVTVLELFRS 265

  Fly   267 PTLRPPLIIGIVMQLSQQFSGINAVFYYSTSLFMSSGLTEESAKFATIGIGAIMVVMTLVSIPLM 331
            |....||:|.||:|||||.|||||||||||.:|..:|:.|..  :||||.|.:..:.|:||:.|:
Mouse   266 PNYVQPLLISIVLQLSQQLSGINAVFYYSTGIFKDAGVQEPI--YATIGAGVVNTIFTVVSLFLV 328

  Fly   332 DRTGRRTLHLYGLGGMFIFSIFITISFLIKEMIDWMSYLSVVATLGFVVFFAVGPGSIPWMITAE 396
            :|.||||||:.|||||.:.|:|:|||.|:|:..:.||::.:||.|.:|.||.:|||.|||.|.||
Mouse   329 ERAGRRTLHMIGLGGMAVCSVFMTISLLLKDDYEAMSFVCIVAILIYVAFFEIGPGPIPWFIVAE 393

  Fly   397 LFSQGPRPSAMAIAVLVNWMANFVVGIGFPSMKTALENYTFLPFSVFLAIFWIFTYKKVPETKNK 461
            ||||||||:|:|:|...||.:||:||:.|||....|..|.|:.|:.||..|.|||:.||||||.:
Mouse   394 LFSQGPRPAAIAVAGCCNWTSNFLVGMLFPSAAAYLGAYVFIIFAAFLIFFLIFTFFKVPETKGR 458

  Fly   462 TFEEILALF--RHNNGRSMLNC-TNSLEPQSMNSG 493
            |||:|...|  :.::|:..... .||::|.....|
Mouse   459 TFEDIARAFEGQAHSGKGPAGVELNSMQPVKETPG 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glut1	NP_612073.2	MFS_GLUT_Class1	15..461	CDD:340989	228/445 (51%)
Slc2a3	NP_001397304.1	MFS_GLUT_Class1	14..458	CDD:340989	230/449 (51%)