Protein Alignment Glut1 and Slc2a2

DIOPT Version :10

• Sequence 1: NP_612073.2
• Gene: Glut1 / 38109
• FlyBaseID: FBgn0264574
• Length: 1440
• Species: Drosophila melanogaster
• Sequence 2: NP_112474.2
• Gene: Slc2a2 / 20526
• MGIID: 1095438
• Length: 523
• Species: Mus musculus
• Alignment Length: 500
• Identity: 212/500 - (42%)
• Similarity: 313/500 - (62%)
• Gaps: 35/500 - (7%)

  Fly     9 LTFFLTYSIFSAVLGMLQFGYNTGVINAPEKNIENFMKDVY------------KDRYGEDI---- 57
            :|..|.:::|:|||...||||:.||||||::.|.:..:.|.            .|..|.|.
Mouse     6 ITGTLAFTVFTAVLSSFQFGYDIGVINAPQEVIISHYRHVLGVPLDDRKAAINYDVNGTDTPLTV 70

  Fly    58 -----------------SEEFIQQLYSVAVSIFAIGGMLGGFSGGWMANRFGRKGGLLLNNVLGI 105
                             |...:..|:|::||.||:|||:..|.|||:.::.||...:|..|.|.:
Mouse    71 TPAYTTPAPWDEEETEGSAHIVTMLWSLSVSSFAVGGMVASFFGGWLGDKLGRIKAMLAANSLSL 135

  Fly   106 AGACLMGFTKVSHSYEMLFLGRFIIGVNCGLNTSLVPMYISEIAPLNLRGGLGTVNQLAVTVGLL 170
            .||.|||.:|...::.::..||.:.|:.|||.:.||||||.||||..|||.|||::|||:..|:|
Mouse   136 TGALLMGCSKFGPAHALIIAGRSVSGLYCGLISGLVPMYIGEIAPTTLRGALGTLHQLALVTGIL 200

  Fly   171 LSQVLGIEQILGTNEGWPILLGLAICPAILQLILLPVCPESPRYLLITKQWEEEARKALRRLRAS 235
            :||:.|:..|||..:.|.|||||:..||:||.:||..||||||||.|..:.|..|:|:|:|||.:
Mouse   201 ISQIAGLSFILGNQDHWHILLGLSAVPALLQCLLLLFCPESPRYLYIKLEEEVRAKKSLKRLRGT 265

  Fly   236 GSVEEDIEEMRAEERAQQSESHISTMELICSPTLRPPLIIGIVMQLSQQFSGINAVFYYSTSLFM 300
            ..|.:||.||:.|:....:|..:|.::|......|.|:::.:::.::|||||||.:||||||:|.
Mouse   266 EDVTKDINEMKKEKEEASTEQKVSVIQLFTDANYRQPILVALMLHMAQQFSGINGIFYYSTSIFQ 330

  Fly   301 SSGLTEESAKFATIGIGAIMVVMTLVSIPLMDRTGRRTLHLYGLGGMFIFSIFITISFLIKEMID 365
            ::|:::  ..:||||:|||.::.|.||:.|:::.|||||.|.|:.|||..:||:::..::.:...
Mouse   331 TAGISQ--PVYATIGVGAINMIFTAVSVLLVEKAGRRTLFLTGMIGMFFCTIFMSVGLVLLDKFA 393

  Fly   366 WMSYLSVVATLGFVVFFAVGPGSIPWMITAELFSQGPRPSAMAIAVLVNWMANFVVGIGFPSMKT 430
            ||||:|:.|...||.||.:|||.|||.:.||.|||||||:|:|:|...||:.|||:.:.|..:..
Mouse   394 WMSYVSMTAIFLFVSFFEIGPGPIPWFMVAEFFSQGPRPTALALAAFSNWVCNFVIALCFQYIAD 458

  Fly   431 ALENYTFLPFSVFLAIFWIFTYKKVPETKNKTFEEILALFRHNNG 475
            .|..|.|..|:..:.:|.:||:.||||||.|:||||.|.||..:|
Mouse   459 FLGPYVFFLFAGVVLVFTLFTFFKVPETKGKSFEEIAAEFRKKSG 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glut1	NP_612073.2	MFS_GLUT_Class1	15..461	CDD:340989	201/478 (42%)
Slc2a2	NP_112474.2	MFS_GLUT_Class1	12..489	CDD:340989	201/478 (42%)