Protein Alignment Glut1 and Y37A1A.3

DIOPT Version :10

• Sequence 1: NP_612073.2
• Gene: Glut1 / 38109
• FlyBaseID: FBgn0264574
• Length: 1440
• Species: Drosophila melanogaster
• Sequence 2: NP_502675.4
• Gene: Y37A1A.3 / 189599
• WormBaseID: WBGene00012536
• Length: 500
• Species: Caenorhabditis elegans
• Alignment Length: 495
• Identity: 124/495 - (25%)
• Similarity: 219/495 - (44%)
• Gaps: 60/495 - (12%)

  Fly     1 MAFLCAPGLTFFLTYSIFSAVLGMLQFGYNTGVINAPEKNIENFMKDVYKDRYGEDISEEFIQQL 65
            ||.:.|.|.:|              .||:...:.|..:.....|:.........:|.....::..
 Worm    27 MAIIVAFGSSF--------------SFGFQLLITNPAQGAFIKFLNASKHSNNPDDNELSHLENE 77

  Fly    66 YSVAVSIFAIGGMLGGFSGGWMANRFGRKGGLLLNNVLGIAGACL--MGFTKVSHSYEMLFL-GR 127
            :|..|:||.:|...|.|....:|.|||||.|::::....:..:.|  :.|..|:|   :||: .|
 Worm    78 WSFIVAIFFLGSATGAFLIKTVAERFGRKKGVIVSLFAQVTSSMLTIVSFWIVNH---ILFIFAR 139

  Fly   128 FIIGVNCGLNTSLVPMYISEIAPLNLRGGLGTVN----QLAVTVGLLLSQVLGIEQILGTNEGWP 188
            |::||...::..:..|:::|.:|...||....:|    ||::|||    .|:.:..:||....|.
 Worm   140 FLMGVGITISMGIAAMFVTESSPAYCRGVSSLINGVLLQLSITVG----AVMAMPNVLGNETHWW 200

  Fly   189 ILLGLAICPAILQLILLPVCPESPRYLLITKQWEEEARKALRRLRASGSVE--EDIEEMRAE--- 248
            .|....:......|::||...|||.| |.::..:.....|:.:.:...||:  ..|.:..||
 Worm   201 YLYLFQLIINTTVLVILPWVHESPSY-LASQDIKHHELHAMFKAKIVASVKFYHGISDPEAEVFA 264

  Fly   249 ----ERAQQSESHISTMELICSPTLRPPLIIGIVMQLSQQFSGINAVFYYSTSLFMSSGLTEESA 309
                |..|.:.|..|.:.:..||..|...::|:::..|...|||..:..::..:.|:.|:.:::|
 Worm   265 DNLIETHQITRSQESIISVWKSPFNRRGTLLGMMVTFSMAMSGITVINAFAFEILMNVGMKQDTA 329

  Fly   310 KFATIGIGAIMVVMTLVSIPLMDRTGRRTLHLYGLGGMFIFSIFIT-ISFLIKEMIDW-MSYLSV 372
            ..|...|........|||..::|..|||.|.:...|.:.:.::.|. :.:...|..:. :||..:
 Worm   330 AIANAAICFFSFAGILVSTKIIDHFGRRPLLISTFGCLAVVNVVIVGLMYTFAETQNQIVSYFLI 394

  Fly   373 VATLGFVVFFAVGPGSIPWMITAELFSQGPRPSAMAIAVLVNWMANFVVGIGFPSMKTALENYT- 436
            .|...|...||:|||.:...||.||..|..|.::......|..:..|::...:..:|    |.|
 Worm   395 SAICMFNFLFAMGPGPLSMFITGELVPQNCRSASSVWTNAVMAVVRFLILTFYLPVK----NMTS 455

  Fly   437 -FLPFSVF---------LAIFWIFTYKKVPETKNKTFEEI 466
             |:.:::|         |.||::     :||||.:..|||
 Worm   456 EFMAYAIFFVVPMIVAVLVIFFL-----LPETKGRNVEEI 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glut1	NP_612073.2	MFS_GLUT_Class1	15..461	CDD:340989	116/474 (24%)
Y37A1A.3	NP_502675.4	MFS_GLUT_Class1_2_like	28..485	CDD:340915	120/487 (25%)